LAMP2 Protein (His tag)
-
- Target See all LAMP2 Proteins
- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
- Protein Type
- Recombinant
-
Origin
- Mouse
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LAMP2 protein is labelled with His tag.
- Purpose
- Recombinant Mouse LAMP2/CD107b Protein (His Tag)
- Sequence
- Leu 26-Asn 379
- Characteristics
- A DNA sequence encoding the mouse LAMP2 (P17047-1) extracellular domain (Leu 26-Asn 379) was fused with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.
- Purity
- > 97 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product LAMP2 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
- Alternative Name
- LAMP2/CD107b (LAMP2 Products)
- Background
-
Background: LAMP2 (Lysosomal-associated membrane protein 2), also known as CD107b (Cluster of Differentiation 107b), is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. In human, LAMP2, the causative gene of Danon disease, located on chromosome Xq24, encodes the lysosome-associated membrane protein-2 (LAMP-2). LAMP-2 deficiency, or Danon disease, is a rare X-linked lysosomal disease characterized by cardiomyopathy, vacuolar myopathy, and mental retardation. LAMP2 cardiomyopathy is an X-linked and highly progressive myocardial storage disorder associated with diminished survival, which clinically resembles sarcomeric hypertrophic cardiomyopathy.
Synonym: CD107b,Lamp-2,Lamp-2a,Lamp-2b,Lamp-2c,LampII,LGP-B,Mac3
- Molecular Weight
- 40.6 kDa
- Pathways
- Autophagy
-