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CD13 Protein (AA 69-966) (His tag)

ANPEP Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7273840
  • Target See all CD13 (ANPEP) Proteins
    CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 69-966
    Origin
    • 7
    • 1
    • 1
    Mouse
    Source
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD13 protein is labelled with His tag.
    Purpose
    Mouse CD13/ANPEP Protein
    Sequence
    Lys69-Ser966
    Characteristics
    Recombinant Mouse CD13/ANPEP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Lys69-Ser966.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
    Alternative Name
    CD13 (ANPEP Products)
    Background
    CD13/aminopeptidase N is a widely expressed ectoenzyme with multiple functions. As an enzyme, CD13 regulates activities of numerous cytokines by cleaving their N-terminals and is involved in Ag processing by trimming the peptides bound to MHC class II. Independent of its enzymatic activity, cell membrane CD13 functions by cross-linking-induced signal transduction, regulation of receptor recycling, enhancement of FcγR-mediated phagocytosis, and acting as a receptor for cytokines.
    Molecular Weight
    103.9 kDa. Due to glycosylation, the protein migrates to 115-130 kDa based on Tris-Bis PAGE result.
    UniProt
    P97449
    Pathways
    Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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