IBSP Protein (AA 17-324) (His tag)

Catalog No. ABIN7273988

Product Details

Target: IBSP (Integrin-Binding Sialoprotein (IBSP))

Protein Type: Recombinant

Protein Characteristics: AA 17-324

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This IBSP protein is labelled with His tag.

Purpose: Mouse BSPII Protein

Sequence: Phe17-Gln324

Characteristics: Recombinant Mouse BSPII Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe17-Gln324.

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: IBSP (Integrin-Binding Sialoprotein (IBSP))

Alternative Name: BSPII (IBSP Products)

Background: Osteopontin (OPN), bone sialoprotein (BSPII), and osteonectin (ON) belong to a family of glycoproteins, which have been linked to cancer metastasis and progression. Here, we report on the selection of antisense oligonucleotides (ASOs), which are effective in reducing their protein levels.

Molecular Weight: 34.9 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.

UniProt: Q61711