IBSP Protein (AA 17-318) (His tag)

Catalog No. ABIN7273986

This Recombinant IBSP protein is produced in HEK-293 Cells.

Quick Overview for IBSP Protein (AA 17-318) (His tag) (ABIN7273986)

Target: IBSP (Integrin-Binding Sialoprotein (IBSP))

Protein Type: Recombinant

Biological Activity: Active

Origin: Cynomolgus

Source: HEK-293 Cells

Purity: > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC

Product Details

Protein Characteristics: AA 17-318

Purification tag / Conjugate: This IBSP protein is labelled with His tag.

Purpose: Cynomolgus BSPII Protein

Sequence: Phe17-Gln318

Characteristics: Recombinant Cynomolgus BSPII Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe17-Gln318.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Cynomolgus BSPII on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Cynomolgus BSPII is greater than 95% as determined by SEC-HPLC.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: IBSP (Integrin-Binding Sialoprotein (IBSP))

Alternative Name: BSPII

Background: IBSP (Integrin Binding Sialoprotein) is a Protein Coding gene. Diseases associated with IBSP include Fibrous Dysplasia and Chondromalacia. Among its related pathways are Degradation of the extracellular matrix and Cytoskeletal Signaling.The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12 % of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts.

Molecular Weight: 34.63 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Bis-Tris PAGE result.

UniProt: A0A2K5UM27