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CPM Protein (AA 18-423) (His tag)

CPM Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274411
  • Target See all CPM Proteins
    CPM (Carboxypeptidase M (CPM))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 18-423
    Origin
    • 7
    • 3
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CPM protein is labelled with His tag.
    Purpose
    Human CPM Protein
    Sequence
    Leu18-Ser423
    Characteristics
    Recombinant Human CPM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu18-Ser423.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product CPM Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CPM (Carboxypeptidase M (CPM))
    Alternative Name
    CPM (CPM Products)
    Synonyms
    im:7143022 Protein, im:7143022l Protein, si:dkey-11p6.1 Protein, zgc:110307 Protein, CPM Protein, 1110060I01Rik Protein, 5730456K23Rik Protein, AA589379 Protein, E030045M14Rik Protein, carboxypeptidase M Protein, carboxypeptidase D Protein, CPM Protein, cpm Protein, LOC5574253 Protein, Cpm Protein
    Background
    Carboxypeptidase M (CPM) is a glycosylphosphatidylinositol anchored enzyme that plays an important role in the kallikrein-kinin system (KKS). CPM catalytic domain hydrolyzes Arg from C-terminal peptides (i.e., bradykinin and kallidin), generating des-Arg-kinins, the agonists of B1 receptor (B1R).
    Molecular Weight
    47.48 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result.
    UniProt
    P14384
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