IGFBP3 Protein (AA 28-291) (His tag)
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- Target See all IGFBP3 Proteins
- IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-291
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IGFBP3 protein is labelled with His tag.
- Purpose
- Human IGFBP-3 Protein
- Sequence
- Gly28-Lys291
- Characteristics
- Recombinant Human IGFBP-3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly28-Lys291.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product IGFBP3 Protein
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Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (Active) protein
IGFBP3 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 120-244) protein (His tag)IGFBP3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 28-291) protein (His tag)IGFBP3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
- Alternative Name
- IGFBP-3 (IGFBP3 Products)
- Background
- Insulin-like growth factor binding protein-3 (IGFBP-3) is a p53 tumor suppressor-regulated protein and a major carrier for IGFs in circulation. Among six high-affinity IGFBPs, which are IGFBP-1 through 6, IGFBP-3 is the most extensively investigated IGFBP species with respect to its IGF/IGF-I receptor (IGF-IR)-independent biological actions beyond its endocrine/paracrine/autocrine role in modulating IGF action in cancer.
- Molecular Weight
- 29.8 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result.
- Pathways
- Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding
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