IGFBP3 Protein (AA 1-291) (His tag)
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- Target See all IGFBP3 Proteins
- IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-291
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IGFBP3 protein is labelled with His tag.
- Sequence
- Met1-Lys291
- Characteristics
- A DNA sequence encoding theHuman IGFBP3 protein (P17936) (Met1-Lys291) was expressed with a C-His.
- Purity
- >80 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product IGFBP3 Protein
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Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (Active) protein
IGFBP3 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 28-291) protein (His tag)IGFBP3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 120-244) protein (His tag)IGFBP3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 28-291) protein (His tag)IGFBP3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 182-291) protein (GST tag)IGFBP3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 28-292) protein (His tag)Crystallography grade IGFBP3 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
- Alternative Name
- IGFBP3 (IGFBP3 Products)
- Synonyms
- BP-53 Protein, IBP3 Protein, AI649005 Protein, IGFBP-3 Protein, IGgfbp3 Protein, IGF-BP3 Protein, zgc:91788 Protein, IGFBP3 Protein, igfbp3 Protein, insulin like growth factor binding protein 3 Protein, insulin-like growth factor binding protein 3 Protein, IGFBP3 Protein, Igfbp3 Protein, igfbp3 Protein, IGFBP-3 Protein, LOC100305016 Protein
- Background
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Background: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. Inhibits the positive effect of humanin on insulin sensitivity.Promotes testicular germ cell apoptosis.
Synonym: IBP-3,IGF-binding protein 3,IGFBP-3
- Molecular Weight
- 32.5 kDa
- UniProt
- P17936
- Pathways
- Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding
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