IL23A Protein (AA 22-196) (His-Avi Tag,Biotin)
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- Target See all IL23A Proteins
- IL23A (Interleukin 23, alpha subunit p19 (IL23A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-196
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL23A protein is labelled with His-Avi Tag,Biotin.
- Purpose
- Biotinylated Mouse IL-23A Protein
- Sequence
- Val22-Ala196
- Characteristics
- Recombinant Biotinylated Mouse IL-23A Protein is expressed from HEK293 with His tag and Avi Tag at the C-Terminus.It contains Val22-Ala196.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product IL23A Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- IL23A (Interleukin 23, alpha subunit p19 (IL23A))
- Alternative Name
- IL-23A (IL23A Products)
- Background
- The heterodimeric cytokine interleukin-23 (IL-23 or IL23A/IL12B) is produced by dendritic cells and macrophages and promotes the proinflammatory and regenerative activities of T helper 17 (Th17) and innate lymphoid cells. A recent study has reported that IL-23 is also secreted by lung adenoma cells and generates an inflammatory and immune-suppressed stroma.
- Molecular Weight
- 22.60 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9EQ14
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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