PVRL2 Protein (AA 32-360) (Fc Tag)
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- Target See all PVRL2 Proteins
- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 32-360
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PVRL2 protein is labelled with Fc Tag.
- Purpose
- Human Nectin-2/CD112 Protein
- Sequence
- Gln32-Leu360
- Characteristics
- Recombinant Human Nectin-2/CD112 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln32-Leu360.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human PVRIG, mFc Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human Nectin-2, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product PVRL2 Protein
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Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 32-360) protein (His-Avi Tag)
PVRL2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 32-351) protein (His tag)PVRL2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 32-360) protein (mFc Tag)PVRL2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) protein (His-Avi Tag,Biotin)PVRL2 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 32-360) protein (His tag)PVRL2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 32-360) (Active) protein (Fc Tag)PVRL2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 32-360) (Active) protein (His tag)PVRL2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 32-360) (Active) protein (Fc Tag,AVI tag,Biotin)PVRL2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 43-182) protein (His tag)PVRL2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 1-479) protein (GST tag)PVRL2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
- Alternative Name
- Nectin-2 (PVRL2 Products)
- Background
- Nectin-2 is an adhesion molecule that has been reported to play a role in tumor growth, metastasis and tumor angiogenesis. Nectin-2 expression in ovarian cancer may support tumor cell adhesion, leading to growth and lymph node metastasis. Effect of VEGF on Nectin-2 expression as well as permeability was investigated in HUVEC.
- Molecular Weight
- 62.3 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization
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