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PLGF Protein (AA 19-158) (His tag)

PGF Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Catalog No. ABIN7275447
  • Target See all PLGF (PGF) Proteins
    PLGF (PGF) (Placenta Growth Factor (PGF))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 19-158
    Origin
    • 19
    • 7
    • 4
    • 3
    • 1
    Mouse
    Source
    • 14
    • 10
    • 4
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PLGF protein is labelled with His tag.
    Purpose
    Mouse PGF Protein
    Sequence
    Val19-Pro158
    Characteristics
    Recombinant Mouse PGF Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val19-Pro158.
    Purity
    > 95 % as determined by Tris-Bis PAGE
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product PGF Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PLGF (PGF) (Placenta Growth Factor (PGF))
    Alternative Name
    PGF (PGF Products)
    Background
    Placental growth factor (PGF) is another member of the VEGF family of cytokines with pro-angiogenic and pro-inflammatory effects. Retinal inhibition of PGF in combination with VEGF-A prevents vascular leakage and CNV possibly via modulating their own expression in mononuclear phagocytes. PGF-related, optimized strategies to target inflammation-mediated angiogenesis may help to increase efficacy and reduce non-responders in the treatment of wet AMD patients.
    Molecular Weight
    16.99 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.
    UniProt
    P49764
    Pathways
    VEGFR1 Specific Signals
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