PLGF Protein (AA 19-170) (His tag)
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- Target See all PLGF (PGF) Proteins
- PLGF (PGF) (Placenta Growth Factor (PGF))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 19-170
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PLGF protein is labelled with His tag.
- Sequence
- AA 19-170
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 20.2 kDa. The protein migrates as 28-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product PGF Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 100 mM Acetic Acid, pH 3.0
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
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- Target
- PLGF (PGF) (Placenta Growth Factor (PGF))
- Alternative Name
- PLGF (PGF Products)
- Synonyms
- D12S1900 Protein, PGFL Protein, PLGF Protein, PlGF-2 Protein, SHGC-10760 Protein, AI854365 Protein, PIGF Protein, Plgf Protein, PlGF Protein, placental growth factor Protein, placenta growth factor Protein, PGF Protein, Pgf Protein, PLGF Protein
- Background
- Placental growth factor (PGF) is also known as vascular endothelial growth factor-related protein, PLGF and PlGF2, is a member of the VEGF (vascular endothelial growth factor) sub-family - a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast. PGF is actived in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. PlGF2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
- Molecular Weight
- 18.2 kDa
- NCBI Accession
- NP_002623
- Pathways
- VEGFR1 Specific Signals
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