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PGLYRP1 Protein (AA 22-196) (Fc Tag)

PGLYRP1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275449
  • Target See all PGLYRP1 Proteins
    PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 22-196
    Origin
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 4
    • 4
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This PGLYRP1 protein is labelled with Fc Tag.
    Purpose
    Human PGLYRP1 Protein
    Sequence
    Gln22-Pro196
    Characteristics
    Recombinant Human PGLYRP1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln22-Pro196.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product PGLYRP1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))
    Alternative Name
    PGLYRP1 (PGLYRP1 Products)
    Background
    Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway.
    Molecular Weight
    46.2 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.
    UniProt
    O75594
    Pathways
    Activation of Innate immune Response
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