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PGLYRP1 Protein (AA 19-182) (Fc Tag)

PGLYRP1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Catalog No. ABIN7275450
  • Target See all PGLYRP1 Proteins
    PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 19-182
    Origin
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    Mouse
    Source
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PGLYRP1 protein is labelled with Fc Tag.
    Purpose
    Mouse PGLYRP1 Protein
    Sequence
    Phe19-Glu182
    Characteristics
    Recombinant Mouse PGLYRP1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe19-Glu182.
    Purity
    > 95 % as determined by Tris-Bis PAGE
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in PBS, 10 % Glycerol ( pH 8.0).
    Storage
    -80 °C
    Storage Comment
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))
    Alternative Name
    PGLYRP1 (PGLYRP1 Products)
    Synonyms
    PGLYRP1 Protein, PGLYRP Protein, pgrp Protein, tag7 Protein, pgrps Protein, pglyrp Protein, pgrp-s Protein, tnfsf3l Protein, MGC108330 Protein, MGC108469 Protein, PGRP-SC1a Protein, si:dkey-113g17.4 Protein, si:ch211-202c21.3 Protein, PGRP Protein, PGRP-S Protein, PGRPS Protein, TAG7 Protein, TNFSF3L Protein, Pglyrp Protein, Tag7 Protein, Tasg7 Protein, Tnfsf3l Protein, Pgrp Protein, peptidoglycan recognition protein 1 Protein, peptidoglycan recognition protein 1 L homeolog Protein, peptidoglycan recognition protein 5 Protein, PGLYRP1 Protein, pglyrp1.L Protein, pglyrp1 Protein, pglyrp5 Protein, Pglyrp1 Protein
    Background
    Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway.
    Molecular Weight
    45.7 kDa. Due to glycosylation, the protein migrates to 50-55 kDa based on Tris-Bis PAGE result.
    UniProt
    O88593
    Pathways
    Activation of Innate immune Response
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