ROR2 Protein (His-Avi Tag,Biotin)
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- Target See all ROR2 Proteins
- ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ROR2 protein is labelled with His-Avi Tag,Biotin.
- Sequence
- Val34-Gly403
- Purity
- > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Anti-ROR2 Antibody, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human ROR2, hFc Tag with the EC50 of 6.5ng/ml determined by ELISA. See testing image for detail.
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Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 34-403) protein (His-Avi Tag)
ROR2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 34-403) protein (Fc Tag)ROR2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 34-403) protein (His tag)ROR2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 34-403) protein (His tag)ROR2 Origin: Mouse Host: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))
- Alternative Name
- ROR2 (ROR2 Products)
- Background
- BDB, BDB1, NTRKR2, ROR2,ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain.
- Molecular Weight
- 44.2 kDa. Due to glycosylation, the protein migrates to 54-65 kDa based on Tris-Bis PAGE result.
- UniProt
- A1L4F5
- Pathways
- RTK Signaling, WNT Signaling
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