DC-SIGN/CD209 Protein (AA 59-404) (His tag)
-
- Target See all DC-SIGN/CD209 (CD209) Proteins
- DC-SIGN/CD209 (CD209) (CD209)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 59-404
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DC-SIGN/CD209 protein is labelled with His tag.
- Purpose
- Human CD209/DC-SIGN Protein
- Sequence
- Gln59-Ala404
- Characteristics
- Recombinant Human CD209/DC-SIGN Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Gln59-Ala404.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.12 μM as determined in SPR assay (Biacore T200). See testing image for detail.
-
CD209 (CD209) protein (Fc Tag)
CD209 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
CD209 (CD209) (AA 1-404) protein (GST tag)CD209 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
CD209 (CD209) (AA 271-380) protein (GST tag)CD209 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- DC-SIGN/CD209 (CD209) (CD209)
- Alternative Name
- CD209 (CD209 Products)
- Background
- C-type lectin CD209/DC-SIGN and CD209L/L-SIGN proteins are distinct cell adhesion and pathogen recognition receptors that mediate cellular interactions and recognize a wide range of pathogens, including viruses such as SARS, SARS-CoV-2, bacteria, fungi and parasites. Pathogens exploit CD209 family proteins to promote infection and evade the immune recognition system.
- Molecular Weight
- 40.5 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result.
-
