CXCR4 Protein (AA 1-38) (His tag)
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- Target See all CXCR4 Proteins
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-38
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CXCR4 protein is labelled with His tag.
- Sequence
- Met1-Lys38
- Characteristics
- A DNA sequence encoding the human CXCR4 (C28A) (1M-38K) was expressed with a GST tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CXCR4 Protein
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Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-352) protein (His tag)
custom-made CXCR4 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Chemokine (C-X-C Motif) Receptor 4 (CXCR4) proteinCXCR4 Origin: Human Host: HEK-293 Cells Synthetic Nanodisc
Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-80) protein (His-IF2DI Tag)CXCR4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-38) protein (Fc Tag)CXCR4 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-352) protein (GST tag)CXCR4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-46) protein (GST tag)CXCR4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-359) protein (His tag)custom-made CXCR4 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
- Alternative Name
- CXCR4 (CXCR4 Products)
- Background
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Abbreviation: CXCR4
Target Synonym: C-X-C chemokine receptor type 4,CD184,FB22,Fusin,HM89,HSY3RR,LAP3,LCR1,NPYR,SDF 1 receptor,WHIM
Background: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin, leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus.
- Molecular Weight
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Calculated MW: 31.2 kDa
Observed MW: 32-35 kDa
- UniProt
- P61073
- Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events
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