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EIF4E Protein (AA 2-217) (GST-His-Tag)

EIF4E Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505312
  • Target See all EIF4E Proteins
    EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 2-217
    Origin
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 5
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This EIF4E protein is labelled with GST-His-Tag.
    Sequence
    Ala 2-Val 217
    Characteristics
    A DNA sequence encoding the Human eIF4E protein (P06730) (Ala 2-Val 217) was expressed with a N-GST&C-His tag.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product EIF4E Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
    Alternative Name
    eIF4E (EIF4E Products)
    Background

    Abbreviation: eIF4E

    Target Synonym: Eukaryotic translation initiation factor 4E,eIF-4E,eIF-4F 25 kDa subunit,mRNA cap-binding protein,EIF4E,EIF4EL1,EIF4F

    Background: Eukaryotic translation initiation factor 4E is a 217 amino acids protein that belongs to the eukaryotic initiation factor 4E family. eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. EIF4E is also known to interact with other partners.It can recognize and bind the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

    Molecular Weight

    Calculated MW: 48.65 kDa

    Observed MW: 52 kDa

    UniProt
    P06730
    Pathways
    BCR Signaling
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