SLC30A6 Protein (AA 1-461) (His tag)

Catalog No. ABIN7545418

Product Details

Target: SLC30A6 (Solute Carrier Family 30 (Zinc Transporter), Member 6 (SLC30A6))

Protein Type: Recombinant

Protein Characteristics: AA 1-461

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This SLC30A6 protein is labelled with His tag.

Purpose: Custom-made recombinant SLC30A6 Protein expressed in mammalian cells.

Sequence: MGTIHLFRKP QRSFFGKLLR EFRLVAADRR SWKILLFGVI NLICTGFLLM WCSSTNSIAL TAYTYLTIFD LFSLMTCLIS YWVTLRKPSP VYSFGFERLE VLAVFASTVL AQLGALFILK ESAERFLEQP EIHTGRLLVG TFVALCFNLF TMLSIRNKPF AYVSEAASTS WLQEHVADLS RSLCGIIPGL SSIFLPRMNP FVLIDLAGAF ALCITYMLIE INNYFAVDTA SAIAIALMTF GTMYPMSVYS GKVLLQTTPP HVIGQLDKLI REVSTLDGVL EVRNEHFWTL GFGSLAGSVH VRIRRDANEQ MVLAHVTNRL YTLVSTLTVQ IFKDDWIRPA LLSGPVAANV LNFSDHHVIP MPLLKGTDDL NPVTSTPAKP SSPPPEFSFN TPGKNVNPVI LLNTQTRPYG FGLNHGHTPY SSMLNQGLGV PGIGATQGLR TGFTNIPSRY GTNNRIGQPR P Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: SLC30A6 (Solute Carrier Family 30 (Zinc Transporter), Member 6 (SLC30A6))

Alternative Name: SLC30A6 (SLC30A6 Products)

Background: Zinc transporter 6 (ZnT-6) (Solute carrier family 30 member 6),FUNCTION: Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway (PubMed:15994300, PubMed:19366695, PubMed:19759014). As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis (PubMed:15994300, PubMed:19759014, PubMed:35525268). {ECO:0000269|PubMed:15994300, ECO:0000269|PubMed:19366695, ECO:0000269|PubMed:19759014, ECO:0000269|PubMed:35525268}.

Molecular Weight: 51.1 kDa

UniProt: Q6NXT4

Pathways: Peptide Hormone Metabolism, SARS-CoV-2 Protein Interactome