DCST1 Protein (AA 1-732) (His tag)
custom-made
DCST1
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all DCST1 Proteins
- DCST1 (DC-STAMP Domain Containing 1 (DCST1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-732
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DCST1 protein is labelled with His tag.
- Purpose
- Custom-made recombinant Dcst1 Protein expressed in mammalian cells.
- Sequence
- MAFLSSTLHS LGIFEKISRI KEVLKNRLLD LTKRRDQARE QQRKRPHTII QGLLLWSLPV SWIRFLWRQP GEFPVTAFLL GAGTGGLLAI GLFQLLVNPM NIYEEQKVVA LYCLASLGAI GWGTSPHIRC ASLLLVPKML GKEGRLFVMG YALAAIYSGP AANLRSNINE VIASLGCTVE LQINNTRSAW RVSTAPLRAV FKGMVGSKDS LNKEIQNVST SFEEMDEQVK SDAGYSSEDW DKNRESTEMF GTSRVRPYLS TQMVYELRTR LRCIHVVNKA ILSCYRWFDK KHKNCMRRIH LPLFNNMICV PMKFKFLCNI AKVIEIWCYK RIPVEGNFGQ TYDSVNQSIH GLSGEFSANI NLKEEKQSSM VGLNTTNWEH MGTEVRDYVR QQETYLQWAM GLLHVLLSCT FLLVFHSAFS YMDHYNWDIR FDNIYISTYF CQIDARRKKL GKQSLLPLRK AERKTVIFPF KATIQAWEMR YVIRELLETL PIVLLLLVLC AIDWALYSVF DTIRQHSFVQ YSFRSSHKLE IKVEGDSILA KLLRKTIGAL NTSSSTDVET NNMPCLPQPI SLNARDYFKA SLPTLLLVCL CLAQAFGYRL RRVIAAFYFP KREKKRALFF YNEFLKKRSA FTKLRRAAIV RRANQQKAPP HYLVEALYRR CPLLHRFMRQ RCVVCQAMET PDSYVCPTPD CKALYCRSCW DDMQRLCPVC TPREELSSSA HSDSNDDAVY GD Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product DCST1 Protein
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- DCST1 (DC-STAMP Domain Containing 1 (DCST1))
- Alternative Name
- Dcst1 (DCST1 Products)
- Background
- E3 ubiquitin-protein ligase DCST1 (EC 2.3.2.27) (DC-STAMP domain-containing protein 1) (RING-type E3 ubiquitin transferase),FUNCTION: E3 ubiquitin-protein ligase which mediates 'Lys-48'-linked ubiquitination of STAT2 and induces its proteasomal degradation thereby negatively regulating type-I-interferon signaling. {ECO:0000250|UniProtKB:Q5T197}., FUNCTION: Essential sperm cell-surface protein required for sperm-egg fusion and fertilization. {ECO:0000269|PubMed:33871360, ECO:0000269|PubMed:35393517}.
- Molecular Weight
- 84.3 kDa
- UniProt
- Q059Y8
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