SLC25A21 Protein (AA 1-298) (His tag)

Catalog No. ABIN7559029

Product Details

Target: SLC25A21 (Slc25a21) (Solute Carrier Family 25 (Mitochondrial Oxodicarboxylate Carrier), Member 21 (Slc25a21))

Protein Type: Recombinant

Protein Characteristics: AA 1-298

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This SLC25A21 protein is labelled with His tag.

Purpose: Custom-made recombinant Slc25a21 Protein expressed in mammalian cells.

Sequence: MSASNVSLLH ETSRQVAAGG SAGLVEICLM HPLDVVKTRF QVQRSVTDPQ SYRTVRGSFQ MIFRTEGLFG FYKGIIPPIL AETPKRAVKF STFELYKKFL GYMSLSPGLT FLIAGLGSGL TEAVVVNPFE VVKVGLQVNR NLFKEQPSTF AYARQIIKKE GLGFQGLNKG LTATLGRHGI FNMVYFGFYH NVKNIIPSSK DPTLEFLRKF GIGFVSGTMG SVFNIPFDVA KSRIQGPQPV PGEIKYRSCF KTMEMIYREE GILALYKGLV PKVMRLGPGG GVMLLVYEYT YAWLQENW Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: SLC25A21 (Slc25a21) (Solute Carrier Family 25 (Mitochondrial Oxodicarboxylate Carrier), Member 21 (Slc25a21))

Alternative Name: Slc25a21 (Slc25a21 Products)

Background: Mitochondrial 2-oxodicarboxylate carrier (Solute carrier family 25 member 21),FUNCTION: Transports dicarboxylates across the inner membranes of mitochondria by a counter-exchange mechanism. Can transport 2-oxoadipate (2-oxohexanedioate), 2-oxoglutarate, adipate (hexanedioate), glutarate, and to a lesser extent, pimelate (heptanedioate), 2-oxopimelate (2-oxoheptanedioate), 2-aminoadipate (2-aminohexanedioate), oxaloacetate, and citrate. Plays a central role in catabolism of lysine, hydroxylysine, and tryptophan, by transporting common metabolite intermediates (such as 2-oxoadipate) into the mitochondria, where it is converted into acetyl-CoA and can enter the citric acid (TCA) cycle. {ECO:0000250|UniProtKB:Q9BQT8}.

Molecular Weight: 33.2 kDa

UniProt: Q8BZ09

AlphaFold: Q8BZ09

Pathways: SARS-CoV-2 Protein Interactome