IRAK2 Protein (AA 1-622) (His tag)
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- Target See all IRAK2 Proteins
- IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-622
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IRAK2 protein is labelled with His tag.
- Purpose
- Custom-made recombinant Irak2 Protein expressed in mammalian cells.
- Sequence
- MACYIYQLPS WVLDDLCRNI DTLSEWDWMQ FASYVITDLT QLRKIKSMER VQGVSITREL LWWWSMRQAT VQQLVDLLCH LELYRAAQIV LSWKPVPEST SPLPAFPEAV KPGAVATSRR NLKDEQEKVR PVKPRSLLDT GPIMAGAQRQ RPCEMDAPCS LKTDAPDSPQ SKYCSTSTSA PKQERLLGLP GDRLFWSEAD VVQATEDFDQ SHRISEGTFA DIYQGQRNGV AFAFKKLREV AGSSPGSMDR FLQAEMQLCL RCCHANVLPL LGFCTGRQFH SLIYPYMANG SLHDRLWAQG NSDMLPWPQR ASICSGLLLA VEHLHSLDII HSNVKSANVL LDQHLNPKLA HPVAHPHPDN KKTKYTVMRT HLFQASAAYL PEHFIRVGQL TKQVDIFSCG IVLAEVLTGI PAMDKDRSPV YLKDLLLSEI PNSTSSVCSR KTSMGKAVVK EICQRHVEKR AGLLPEACEE AWATAVSVCL RRRNASVEEA RVSLAGVEEQ LRGQLSLPWS RVSEATGSSS NTPEETDDVD NSSLSVPSLV MMASCPGAAS SPLFTGHGAA QPSTSGRQEA DSSSEACTGP QTPQNATETS WKIEINEAKR RLMENIVLYK EERLDSSELF GP Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product IRAK2 Protein
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Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (AA 1-625) protein (His tag)
custom-made IRAK2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (AA 416-625) protein (GST tag)IRAK2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (AA 111-210) protein (GST tag)IRAK2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))
- Alternative Name
- Irak2 (IRAK2 Products)
- Background
- Interleukin-1 receptor-associated kinase-like 2 (IRAK-2) (mu-IRAK-2),FUNCTION: Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. {ECO:0000250}.
- Molecular Weight
- 69.0 kDa
- UniProt
- Q8CFA1
- AlphaFold
- Q8CFA1
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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