RASA4 Protein (AA 1-802) (His tag)
custom-made
RASA4
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all RASA4 products
- RASA4 (RAS P21 Protein Activator 4 (RASA4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-802
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RASA4 protein is labelled with His tag.
- Purpose
- Custom-made recombinant Rasa4 Protein expressed in mammalian cells.
- Sequence
- MAKRSSLSIR IVEGKNLPAK DITGSSDPYC IVKVDNEPII RTATVWKTLC PFWGEDYQVH LPPTFHTVAF YVMDEDALSR DDVIGKVCLT RDALASHPKG FSGWTHLVEV DPNEEVQGEI HLRLEVVPGV HASRLRCAVL EARDLAPKDR NGASDPFVRV HYNGRTQETS VVKKSCYPRW NETFDFELEK GASEALLVEA WDWDLVSRND FLGKVAVNVQ RLCSAQQEEG WFRLQPDQSK SRQGKGNLGS LQLEVRLRDE TVLPSVCYQP LVQLLCQEVK LGTQGPGRLI PVIEETTSAE CRQEVATTLL KLFLGQGLAK DFLDLLFQLE LGRTSEANTL FRSNSLASKS MESFLKVAGM RYLHGILGPI IDRVFEEKKY VELDPSKVEV KDVGCSGLHR PQTEAEVLEQ SAQTLRAHLV ALLSAICRSV RTCPAIIRAT FRQLFRRVRE RFPNAQHQNV PFIAVTSFLC LRFFSPAILS PKLFHLRERH ADARTSRTLL LLAKAVQNIG NMDTPVSRAK ESWMEPLQPT VRQGVAQLKD FIMKLVDIEE KEELDLQRAL NSQAPPVKEG PLFIHRTKGK GPLASSSFKK LYFSLTTEAL SFAKTSSSKK STFIKLASIR AAEKVEEKSF GSSHIMQVIY ADDVGRAQTV YLQCKCVNEL NQWLSALRKA STNNRGLLRS YHPGIFRGDK WSCCHQKDKT DQGCDKTHSR VTLQEWNDPL DHDLEAQLIY RHLLGVEAAL RERYQLLRGA TEAGVSPTGC DGAPEDSLAQ LLRVLQDLRE AHGSSLASPA AREPHHLLEL QT Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- RASA4 (RAS P21 Protein Activator 4 (RASA4))
- Alternative Name
- Rasa4 (RASA4 Products)
- Background
- Ras GTPase-activating protein 4 (Calcium-promoted Ras inactivator) (Ras p21 protein activator 4) (RasGAP-activating-like protein 2),FUNCTION: Ca(2+)-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulus that elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis. Isoform 2 activates the Ras pathway and promotes RANKL shedding by modulating the expression of MMP14. {ECO:0000269|PubMed:16041389, ECO:0000269|PubMed:16234249}.
- Molecular Weight
- 90.1 kDa
- UniProt
- Q6PFQ7
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