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RASA4 Products

(RAS P21 Protein Activator 4 (RASA4))

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This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured RASA4 Categories

RASA4 Antibodies

High quality antibodies with extensive validation data.

Recommended RASA4 Antibodies

Product
Reactivity
Application
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Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
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Cat. No. ABIN7167152
Quantity 100 μL
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Reactivity Human, Mouse
Application WB, ELISA
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Cat. No. ABIN6264646
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Reactivity Human, Mouse, Rat
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Cat. No. ABIN6241863
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Recommended RASA4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
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Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3094909
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3135803
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Latest Publications for our RASA4 products

Lockyer, Kupzig, Cullen: "CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway." in: Current biology : CB, Vol. 11, Issue 12, pp. 981-6, (2001) (PubMed).

Synonyms and alternative names related to RASA4

RAS p21 protein activator 4 (RASA4), RAS p21 protein activator 4 (Rasa4), AA793972, AW112107, BB079060, CAPRI, GAPL, mKIAA0538

Protein level used designations for RASA4

  • Ca2+-promoted Ras inactivator
  • calcium-promoted Ras inactivator
  • ras GTPase-activating protein 4
  • rasGAP-activating-like protein 2
  • Ca2+promoted Ras inactivator
  • calcium-promoted RAS inactivator
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