COL18A1 Protein
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- Target See all COL18A1 Proteins
- COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Yeast (Pichia pastoris)
- Characteristics
- Determined by Endothelial Cell Tube Formation. The cells treated with 10myg/ml Endostatin showed significant anti-angiogenesis effect.
- Purity
- > 97 % by SDS-PAGE
- Endotoxin Level
- level is less than 0.1 ng per myg (1EU/myg) of Endostatin
- Top Product
- Discover our top product COL18A1 Protein
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Collagen, Type XVIII, alpha 1 (COL18A1) protein (His tag)
COL18A1 Origin: Mouse Host: Human Cells Recombinant > 90 % as determined by SDS-PAGE
Collagen, Type XVIII, alpha 1 (COL18A1) protein (KLH)COL18A1 Origin: Human Host: Synthetic > 95 % SDS, WB, ELISA, IP
Collagen, Type XVIII, alpha 1 (COL18A1) (Transcript Variant 2) (Active) proteinCOL18A1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
Collagen, Type XVIII, alpha 1 (COL18A1) (AA 1578-1754) protein (GST tag)COL18A1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Collagen, Type XVIII, alpha 1 (COL18A1) (AA 1578-1754) protein (His tag)COL18A1 Origin: Human Host: Yeast Recombinant > 90 % SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Storage
- -20 °C
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- Target
- COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
- Alternative Name
- Endostatin (COL18A1 Products)
- Target Type
- Chemical
- Background
- Endostatin is a cleaved product of the carboxyl-terminal domain of collagen XVIII. It functions as an anti-angiogenic cytokine that is expressed in various organs especially with high levels in liver, lung, and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant Endostatin expressed in yeast, whichcauses G1 arrest of endothelial cells. Endostatin treatment results in apoptosis of HUVE and HMVE cells. Recombinant human Endostatin is a 20.2 kDa protein consisting of 184 amino acid residues. Synonym: Endostatin 3 3 . Formulation: The sterile filtered solution was lyophilized with 17 mM citric-phosphate buffer, pH 6.2. .
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