Adducin 2 (Beta) ELISA Kits
2 Adducin 2 (Beta) (ADD2) ELISA Kits from 2 manufacturers are available on www.antibodies-online.com.
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Adducin 2 (Beta) (ADD2) ELISA Kit ELISA Kit
Adducin 2 (Beta) (ADD2) ELISA Kit ELISA Kit
Adducin 2 (Beta) (ADD2) Antigen Profile
Protein Summary
Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced transcript variants have been described.
Alternative names and synonyms associated with Adducin 2 (Beta) (ADD2)
- adducin 2 (ADD2) antibody
- adducin 2 (beta) (add2) antibody
- adducin 2 (add2) antibody
- adducin 2 (beta) (Add2) antibody
- adducin 2 (Add2) antibody
- 2900072M03Rik antibody
- add97 antibody
- ADDB antibody
- beta-ADD antibody
- si:dkey-202n14.5 antibody
Protein level used designations for Adducin 2 (Beta) (ADD2) ELISA Kits
adducin 2 (beta) , beta-adducin , erythrocyte adducin subunit beta , beta-adducin-like , snoRNA MBII-396 , adducin beta , adducin-63
GENE ID | SPECIES |
---|---|
459305 | Pan troglodytes |
570147 | Danio rerio |
702939 | Macaca mulatta |
100125042 | Xenopus (Silurana) tropicalis |
100174677 | Pongo abelii |
100348972 | Oryctolagus cuniculus |
100402289 | Callithrix jacchus |
100483326 | Ailuropoda melanoleuca |
100032839 | Monodelphis domestica |
100050348 | Equus caballus |
100564223 | Anolis carolinensis |
100607928 | Nomascus leucogenys |
100624449 | Sus scrofa |
119 | Homo sapiens |
610670 | Canis lupus familiaris |
518896 | Bos taurus |
11519 | Mus musculus |
24171 | Rattus norvegicus |
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