Browse our anti-CXCL12 (CXCL12) Antibodies

Full name:: anti-Chemokine (C-X-C Motif) Ligand 12 Antibodies (CXCL12)

On www.antibodies-online.com are 190 Chemokine (C-X-C Motif) Ligand 12 (CXCL12) Antibodies from 28 different suppliers available. Additionally we are shipping CXCL12 Proteins (108) and CXCL12 Kits (89) and many more products for this protein. A total of 398 CXCL12 products are currently listed.

Synonyms:: CXCL1, cxcl12, FSP, GRO, GRO1, GROa, IRH, MGSA, MGSA-a, NAP-3, Pbsf, SCYB1, Scyb12, SDF-1, sdf-1a, sdf1, sdf1a, Tlsf, Tpar1, wu:fa55e10, wu:fc16h12, wu:fj84c02, xSDF-1

list all antibodies	Gene Name	GeneID	UniProt
	CXCL12	2919	P09341
	CXCL12	20315	P40224
	CXCL12	24772
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Most Popular Reactivities for anti-CXCL12 (CXCL12) Antibodies

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anti-Human CXCL12 Antibodies:

anti-Mouse (Murine) CXCL12 Antibodies:

anti-Rat (Rattus) CXCL12 Antibodies:

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Relevant Pathways for anti-CXCL12 Antibodies

Negative Regulation of intrinsic apoptotic Signaling

More product categories related to CXCL12 Antibody

Top referenced anti-CXCL12 Antibodies

Human Monoclonal CXCL12 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4899704 : Villalba, Salvucci, Aoki, De La Luz Sierra, Gupta, Davis, Wyvill, Little, Yarchoan, Tosato: Serum inactivation contributes to the failure of stromal-derived factor-1 to block HIV-I infection in vivo. in Journal of leukocyte biology 2003 (PubMed)
Show all 39 Pubmed References
Human Monoclonal CXCL12 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4899705 : Lisignoli, Cristino, Piacentini, Cavallo, Caplan, Facchini: Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54. in Journal of cellular physiology 2006 (PubMed)
Show all 39 Pubmed References
Human Monoclonal CXCL12 Primary Antibody for FACS - ABIN4896548 : Hoellenriegel, Zboralski, Maasch, Rosin, Wierda, Keating, Kruschinski, Burger: The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization. in Blood 2014 (PubMed)
Show all 5 Pubmed References
Human Polyclonal CXCL12 Primary Antibody for IF (p), IHC (p) - ABIN1386329 : Pei, Zeng, Han, Liao, Zhou, Li, Zhang, Liu, Zhang, Liu, Yao, Xu: Renal interstitial infiltration and tertiary lymphoid organ neogenesis in IgA nephropathy. in Clinical journal of the American Society of Nephrology : CJASN 2014 (PubMed)
Show all 3 Pubmed References
Human Polyclonal CXCL12 Primary Antibody for ELISA, Func - ABIN4301060 : Nistala, Habibi, Aroor, Sowers, Hayden, Meuth, Knight, Hancock, Klein, DeMarco, Whaley-Connell: DPP4 inhibition attenuates filtration barrier injury and oxidant stress in the zucker obese rat. in Obesity (Silver Spring, Md.) 2014 (PubMed)
Show all 2 Pubmed References
Human Polyclonal CXCL12 Primary Antibody for EIA, Func - ABIN116230 : Schlaepfer, Audigé, Joller, Speck: TLR7/8 triggering exerts opposing effects in acute versus latent HIV infection. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
Human Polyclonal CXCL12 Primary Antibody for Func, IHC (p) - ABIN2476433 : Prociv, Walker, Whitby: Human ectopic fascioliasis in Australia: first case reports. in The Medical journal of Australia 1992 (PubMed)
Show all 3 Pubmed References

More Antibodies against CXCL12 Interaction Partners

Human Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

a defect of CXCL12 promoter histone acetylation may represent an additional process participating in CXCL12 expression extinction in colon cancer
The findings indicated that SDF-1alpha/CXCR4 (show CXCR4 Antibodies) signaling pathway might be associated with the clinicopathological features and prognosis of patients with nasopharyngeal carcinoma.
CXCL12-CXCR7 (show CXCR7 Antibodies) axis accelerates migration and invasion of pancreatic cancer cells through mTOR (show FRAP1 Antibodies) and Rho/ROCK pathways, and predicts poor prognosis of pancreatic cancer
the role of CXCL12 in multiple sclerosis, with an emphasis on CXCL12 serum concentrations and its gene polymorphism at position +801 (Review)
GROA (show CXCL1 Antibodies) overexpression is associated with invasion in triple negative breast cancer.
nitration on Tyr7 under inflammatory conditions is a novel natural posttranslational regulatory mechanism of CXCL12 which may downregulate the CXCR4 (show CXCR4 Antibodies)-mediated inflammatory and tumor-promoting activities of CXCL12
this study shows that stem cell autocrine CXCL12/CXCR4 (show CXCR4 Antibodies) stimulates invasion and metastasis of esophageal cancer
The CXCR7 (show CXCR7 Antibodies)/CXCL12 axis is involved in lymph node and liver metastasis of gastric cancer.
The results of the transwell chemotaxis assay also supported the above results. Our data suggest that APN (show ANPEP Antibodies) can promote h-JBMMSC chemotaxis by up-regulating CXCL1 (show CXCL1 Antibodies) and CXCL8 (show IL8 Antibodies)
SDF-1 level was significantly elevated in the subchondral bone of human osteoarthritis samples. In the cell studies, the results showed SDF-1 plays an important role in osteogenic differentiation of mesenchymal stem cells.

Rhesus Monkey Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

these results demonstrate that a cross-talk exists between the TGF-beta1 (show TGFB1 Antibodies) and SDF-1 pathways in choroid-retinal endothelial cells
following optic nerve crush, the levels of endogenous SDF-1alpha and CXCR4 (show CXCR4 Antibodies) increase in the retina and optic nerve, where activated glial cells may act as a source of increased SDF-1alpha protein.
The CXCR7 (show CXCR7 Antibodies)/CXCR4 (show CXCR4 Antibodies)/CXCL12 axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.

Mouse (Murine) Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

a defect of CXCL12 promoter histone acetylation may represent an additional process participating in CXCL12 expression extinction in colon cancer
The structure of murine germinal centers (GC) and the localization of GC B (show NPR2 Antibodies) cells are impaired when CXCL12 is unable to bind to cellular or extracellular surfaces.
These findings indicate that the CXCL12alpha-CXCR4 (show CXCR4 Antibodies) axis plays an important role in the regeneration of the neuromuscular junction after motor axon injury.
Here, we show that cabozantinib rapidly eradicates invasive, poorly differentiated PTEN/p53 (show TP53 Antibodies)-deficient murine prostate cancer. This was associated with enhanced release of neutrophil chemotactic factors from tumor cells, including CXCL12 and HMGB1 (show HMGB1 Antibodies), resulting in robust infiltration of neutrophils into the tumor.
nitration on Tyr7 under inflammatory conditions is a novel natural posttranslational regulatory mechanism of CXCL12 which may downregulate the CXCR4 (show CXCR4 Antibodies)-mediated inflammatory and tumor-promoting activities of CXCL12
SDF-1 is secreted shortly after UPEC infection initiating immune cell accumulation.
The data suggest that SDF-1beta provides synergistic effects supporting BMP-2 (show BMP2 Antibodies)-induced, BMSC-mediated bone formation and appears suitable for optimization of bone augmentation in combination therapy protocols.
Hyaluronic acid-laminin hydrogels increase neural stem cell transplant retention and migratory response to SDF-1alpha in a manner critically dependent on signaling via the SDF-1alpha-CXCR4 (show CXCR4 Antibodies) axis.
The Function of SDF-1-CXCR4 Axis in SP Cells-Mediated Protective Role for Renal Ischemia/Reperfusion Injury by SHH/GLI1-ABCG2 Pathway
Adora2B (show ADORA2B Antibodies) stimulation promotes FGF2 (show FGF2 Antibodies) and CXCL12 expression in FAP (show FAP Antibodies)-positive melanoma-associated (show ZNF654 Antibodies) fibroblasts, contributing to the creation of a tumor-promoting microenvironment.

Cow (Bovine) Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

Findings indicate that stromal fibroblasts within mammary glands with mastitis contribute to EMT (show ITK Antibodies) and inflammatory responses of epithelial cells through the secretion of SDF-1, which could result in the inflammation spread and fibrosis within mammary gland.
There is a potential link between follicular SDF1/CXCR4 (show CXCR4 Antibodies) activation and the regulation of ovulation-related genes in cows and horses.
Polymorphism of intron 2 of the SDF1 gene in Galloway, Hereford, and Russian Black Pied cattle

Xenopus laevis Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

expression patterns of xSDF-1a, xCXCR4, and xCXCR7 during gastrulation; results suggest SDF-1 signaling supports migration of the mesendoderm cell cohort toward the animal pole and that activin/nodal signaling acts as a regulator of the expression of xSDF-1a and xCXCR4, but not xCXCR7
SDF-1/CXCR4 chemokine (show CCL1 Antibodies) signaling is involved in the migration and survival or in the differentiation of PGCs in Xenopus
A significant increase of stromal cell-derived factor-1alpha and CXCR4 was observed in protein extracts of idiopathic inflammatory myopathies in comparison with normal controls.
SDF-1 signaling is necessary for migrations of massive numbers of cells during gastrulation.

Pig (Porcine) Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

Polymorphisms in CXCL12 are significantly associated with immunological traits in Landrace piglets and have potential application value for marker-assisted selection of pig breeding with disease resistance.
The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1/CXCR4 (show CXCR4 Antibodies) axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.

Zebrafish Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

Study demonstrates that forced expression of Sdf1a in the fish embryo during early development is an effective strategy to disrupt primordial germ cell migration and produce large populations of infertile fish.
miR (show MYLIP Antibodies)-126a directs lymphatic endothelial cell sprouting and extension by interacting with Cxcl12a-mediated chemokine (show CCL1 Antibodies) signaling and Vegfc (show VEGFC Antibodies)-Flt4 (show FLT4 Antibodies) signal axis.
filopodia distribution and their dynamics are dictated by the gradient of the chemokine (show CCL1 Antibodies) Cxcl12a.
SDF1a directly controls the migration of both leading and trailing edges of a tissue through the activation of two independent receptors, CXCR4b and CXCR7 (show CXCR7 Antibodies).
Prospective isolation and culture of sdf1(DsRed) perivascular cells demonstrated properties consistent with mesenchymal stem cells.
Study shows that the primordium generates an attractant gradient across itself by sequestering Sdf1a protein in its rear via Cxcr7 (show CXCR7 Antibodies)-mediated chemokine (show CCL1 Antibodies) uptake. This self-generated attractant gradient, combined with the route information provided by the stripe of sdf1a-expressing cells, then provides directional guidance to the migrating primordium.
gata4 (show GATA4 Antibodies) gene regulates sdf1a levels during early embryogenesis
These findings suggest an "attractive path" model in which migrating cells closely follow a dynamic SDF1a source that is refined on a transcript and protein level by miR (show MYLIP Antibodies)-430 and Cxcr7b, respectively.
sdf-1 expression and function in the adult zebrafish have important similarities to mammals
Expression of Cxcl12 and Cxclr4 in radial glial cells of the adult zebrafish brain supports important roles for the Cxcl12/Cxcr4 (show CXCR4 Antibodies) pair in brain development and functioning.

CXCL12 Antigen Profile

Antigen Summary

This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CXCL12

C-X-C motif chemokine ligand 1 (CXCL1) antibody
C-X-C motif chemokine ligand 12 (CXCL12) antibody
C-X-C motif chemokine ligand 12 (cxcl12) antibody
chemokine (C-X-C motif) ligand 12 (Cxcl12) antibody
C-X-C motif chemokine ligand 12 (Cxcl12) antibody
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (GRO1) antibody
C-X-C motif chemokine ligand 12 L homeolog (cxcl12.L) antibody
chemokine (C-X-C motif) ligand 1 (Cxcl1) antibody
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (CXCL1) antibody
chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) (cxcl12a) antibody

CXCL1 antibody
cxcl12 antibody
FSP antibody
GRO antibody
GRO1 antibody
GROa antibody
IRH antibody
MGSA antibody
MGSA-a antibody
NAP-3 antibody
Pbsf antibody
SCYB1 antibody
Scyb12 antibody
SDF-1 antibody
sdf-1a antibody
sdf1 antibody
sdf1a antibody
Tlsf antibody
Tpar1 antibody
wu:fa55e10 antibody
wu:fc16h12 antibody
wu:fj84c02 antibody
xSDF-1 antibody

Protein level used designations for CXCL12

, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , C-X-C motif chemokine 1 GRO-alpha(1-73) GRO1 oncogene (melanoma growth stimulating activity, alpha) GRO1 oncogene (melanoma growth-stimulating activity) MGSA alpha fibroblast secretory protein growth-regulated alpha protein melanoma growth stimulatory activity alpha neutrophil-activating protein 3 intercrine reduced in hepatomas pre-B cell growth-stimulating factor stromal cell-derived factor 1 chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) chemokine CXCL12/SDF-1ALPHA stromal cell-derived factor 1 isoform alpha stromal cell-derived factor 1 isoform gamma CXCL12 12-O-tetradecanoylphorbol 13-acetate repressed protein 1 pre-B-cell growth-stimulating factor thymic lymphoma cell-stimulating factor SDF-1 gamma Stromal cell-derived factor 1 stromal cell-derived factor-1 gamma GRO-alpha growth related gene 1 growth-regulated protein homolog alpha C-X-C motif chemokine 12 stromal-derived factor 1 chemokine ligand 12b stromal cell derived factor 1 stromal cell-derived factor-1 beta CXC chemokine CXCL12 chemokine growth regulated protein GRO chemokine ligand 12 unm t30516 unm_t30516

GENE ID	SPECIES
2919	Homo sapiens
6387	Homo sapiens
574334	Macaca mulatta
100173045	Pongo abelii
100304642	Ictalurus punctatus
20315	Mus musculus
24772	Rattus norvegicus
281212	Bos taurus
399030	Xenopus laevis
395180	Gallus gallus
449622	Canis lupus familiaris
494460	Sus scrofa
613811	Bos taurus
493806	Felis catus
100135510	Cavia porcellus
443380	Ovis aries
100721137	Cavia porcellus
352944	Danio rerio

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Show all anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) Antibodies with Pubmed References