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anti-Human CXCL12 Antibodies:
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Human Monoclonal CXCL12 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4899704
Villalba, Salvucci, Aoki, De La Luz Sierra, Gupta, Davis, Wyvill, Little, Yarchoan, Tosato: Serum inactivation contributes to the failure of stromal-derived factor-1 to block HIV-I infection in vivo. in Journal of leukocyte biology 2003
Show all 39 Pubmed References
Human Monoclonal CXCL12 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4899705
Lisignoli, Cristino, Piacentini, Cavallo, Caplan, Facchini: Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54. in Journal of cellular physiology 2006
Show all 39 Pubmed References
Human Monoclonal CXCL12 Primary Antibody for FACS - ABIN4896548
Hoellenriegel, Zboralski, Maasch, Rosin, Wierda, Keating, Kruschinski, Burger: The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization. in Blood 2014
Show all 5 Pubmed References
Human Polyclonal CXCL12 Primary Antibody for IF (p), IHC (p) - ABIN1386329
Pei, Zeng, Han, Liao, Zhou, Li, Zhang, Liu, Zhang, Liu, Yao, Xu: Renal interstitial infiltration and tertiary lymphoid organ neogenesis in IgA nephropathy. in Clinical journal of the American Society of Nephrology : CJASN 2014
Show all 3 Pubmed References
Human Polyclonal CXCL12 Primary Antibody for ELISA, Func - ABIN4301060
Nistala, Habibi, Aroor, Sowers, Hayden, Meuth, Knight, Hancock, Klein, DeMarco, Whaley-Connell: DPP4 inhibition attenuates filtration barrier injury and oxidant stress in the zucker obese rat. in Obesity (Silver Spring, Md.) 2014
Show all 2 Pubmed References
Human Polyclonal CXCL12 Primary Antibody for EIA, Func - ABIN116230
Schlaepfer, Audigé, Joller, Speck: TLR7/8 triggering exerts opposing effects in acute versus latent HIV infection. in Journal of immunology (Baltimore, Md. : 1950) 2006
Human Polyclonal CXCL12 Primary Antibody for Func, IHC (p) - ABIN2476433
Prociv, Walker, Whitby: Human ectopic fascioliasis in Australia: first case reports. in The Medical journal of Australia 1992
Show all 3 Pubmed References
a defect of CXCL12 promoter histone acetylation may represent an additional process participating in CXCL12 expression extinction in colon cancer
The findings indicated that SDF-1alpha/CXCR4 (show CXCR4 Antibodies) signaling pathway might be associated with the clinicopathological features and prognosis of patients with nasopharyngeal carcinoma.
CXCL12-CXCR7 (show CXCR7 Antibodies) axis accelerates migration and invasion of pancreatic cancer cells through mTOR (show FRAP1 Antibodies) and Rho/ROCK pathways, and predicts poor prognosis of pancreatic cancer
the role of CXCL12 in multiple sclerosis, with an emphasis on CXCL12 serum concentrations and its gene polymorphism at position +801 (Review)
GROA (show CXCL1 Antibodies) overexpression is associated with invasion in triple negative breast cancer.
nitration on Tyr7 under inflammatory conditions is a novel natural posttranslational regulatory mechanism of CXCL12 which may downregulate the CXCR4 (show CXCR4 Antibodies)-mediated inflammatory and tumor-promoting activities of CXCL12
this study shows that stem cell autocrine CXCL12/CXCR4 (show CXCR4 Antibodies) stimulates invasion and metastasis of esophageal cancer
The CXCR7 (show CXCR7 Antibodies)/CXCL12 axis is involved in lymph node and liver metastasis of gastric cancer.
The results of the transwell chemotaxis assay also supported the above results. Our data suggest that APN (show ANPEP Antibodies) can promote h-JBMMSC chemotaxis by up-regulating CXCL1 (show CXCL1 Antibodies) and CXCL8 (show IL8 Antibodies)
SDF-1 level was significantly elevated in the subchondral bone of human osteoarthritis samples. In the cell studies, the results showed SDF-1 plays an important role in osteogenic differentiation of mesenchymal stem cells.
these results demonstrate that a cross-talk exists between the TGF-beta1 (show TGFB1 Antibodies) and SDF-1 pathways in choroid-retinal endothelial cells
following optic nerve crush, the levels of endogenous SDF-1alpha and CXCR4 (show CXCR4 Antibodies) increase in the retina and optic nerve, where activated glial cells may act as a source of increased SDF-1alpha protein.
The CXCR7 (show CXCR7 Antibodies)/CXCR4 (show CXCR4 Antibodies)/CXCL12 axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.
The structure of murine germinal centers (GC) and the localization of GC B (show NPR2 Antibodies) cells are impaired when CXCL12 is unable to bind to cellular or extracellular surfaces.
These findings indicate that the CXCL12alpha-CXCR4 (show CXCR4 Antibodies) axis plays an important role in the regeneration of the neuromuscular junction after motor axon injury.
Here, we show that cabozantinib rapidly eradicates invasive, poorly differentiated PTEN/p53 (show TP53 Antibodies)-deficient murine prostate cancer. This was associated with enhanced release of neutrophil chemotactic factors from tumor cells, including CXCL12 and HMGB1 (show HMGB1 Antibodies), resulting in robust infiltration of neutrophils into the tumor.
SDF-1 is secreted shortly after UPEC infection initiating immune cell accumulation.
The data suggest that SDF-1beta provides synergistic effects supporting BMP-2 (show BMP2 Antibodies)-induced, BMSC-mediated bone formation and appears suitable for optimization of bone augmentation in combination therapy protocols.
Hyaluronic acid-laminin hydrogels increase neural stem cell transplant retention and migratory response to SDF-1alpha in a manner critically dependent on signaling via the SDF-1alpha-CXCR4 (show CXCR4 Antibodies) axis.
The Function of SDF-1-CXCR4 Axis in SP Cells-Mediated Protective Role for Renal Ischemia/Reperfusion Injury by SHH/GLI1-ABCG2 Pathway
Adora2B (show ADORA2B Antibodies) stimulation promotes FGF2 (show FGF2 Antibodies) and CXCL12 expression in FAP (show FAP Antibodies)-positive melanoma-associated (show ZNF654 Antibodies) fibroblasts, contributing to the creation of a tumor-promoting microenvironment.
Findings indicate that stromal fibroblasts within mammary glands with mastitis contribute to EMT (show ITK Antibodies) and inflammatory responses of epithelial cells through the secretion of SDF-1, which could result in the inflammation spread and fibrosis within mammary gland.
There is a potential link between follicular SDF1/CXCR4 (show CXCR4 Antibodies) activation and the regulation of ovulation-related genes in cows and horses.
Polymorphism of intron 2 of the SDF1 gene in Galloway, Hereford, and Russian Black Pied cattle
expression patterns of xSDF-1a, xCXCR4, and xCXCR7 during gastrulation; results suggest SDF-1 signaling supports migration of the mesendoderm cell cohort toward the animal pole and that activin/nodal signaling acts as a regulator of the expression of xSDF-1a and xCXCR4, but not xCXCR7
SDF-1/CXCR4 chemokine (show CCL1 Antibodies) signaling is involved in the migration and survival or in the differentiation of PGCs in Xenopus
A significant increase of stromal cell-derived factor-1alpha and CXCR4 was observed in protein extracts of idiopathic inflammatory myopathies in comparison with normal controls.
SDF-1 signaling is necessary for migrations of massive numbers of cells during gastrulation.
Polymorphisms in CXCL12 are significantly associated with immunological traits in Landrace piglets and have potential application value for marker-assisted selection of pig breeding with disease resistance.
The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1/CXCR4 (show CXCR4 Antibodies) axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.
Study demonstrates that forced expression of Sdf1a in the fish embryo during early development is an effective strategy to disrupt primordial germ cell migration and produce large populations of infertile fish.
miR (show MYLIP Antibodies)-126a directs lymphatic endothelial cell sprouting and extension by interacting with Cxcl12a-mediated chemokine (show CCL1 Antibodies) signaling and Vegfc (show VEGFC Antibodies)-Flt4 (show FLT4 Antibodies) signal axis.
filopodia distribution and their dynamics are dictated by the gradient of the chemokine (show CCL1 Antibodies) Cxcl12a.
SDF1a directly controls the migration of both leading and trailing edges of a tissue through the activation of two independent receptors, CXCR4b and CXCR7 (show CXCR7 Antibodies).
Prospective isolation and culture of sdf1(DsRed) perivascular cells demonstrated properties consistent with mesenchymal stem cells.
Study shows that the primordium generates an attractant gradient across itself by sequestering Sdf1a protein in its rear via Cxcr7 (show CXCR7 Antibodies)-mediated chemokine (show CCL1 Antibodies) uptake. This self-generated attractant gradient, combined with the route information provided by the stripe of sdf1a-expressing cells, then provides directional guidance to the migrating primordium.
gata4 (show GATA4 Antibodies) gene regulates sdf1a levels during early embryogenesis
These findings suggest an "attractive path" model in which migrating cells closely follow a dynamic SDF1a source that is refined on a transcript and protein level by miR (show MYLIP Antibodies)-430 and Cxcr7b, respectively.
sdf-1 expression and function in the adult zebrafish have important similarities to mammals
Expression of Cxcl12 and Cxclr4 in radial glial cells of the adult zebrafish brain supports important roles for the Cxcl12/Cxcr4 (show CXCR4 Antibodies) pair in brain development and functioning.
This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
C-X-C motif chemokine 1
, GRO1 oncogene (melanoma growth stimulating activity, alpha)
, GRO1 oncogene (melanoma growth-stimulating activity)
, MGSA alpha
, fibroblast secretory protein
, growth-regulated alpha protein
, melanoma growth stimulatory activity alpha
, neutrophil-activating protein 3
, intercrine reduced in hepatomas
, pre-B cell growth-stimulating factor
, stromal cell-derived factor 1
, chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)
, chemokine CXCL12/SDF-1ALPHA
, stromal cell-derived factor 1 isoform alpha
, stromal cell-derived factor 1 isoform gamma
, 12-O-tetradecanoylphorbol 13-acetate repressed protein 1
, pre-B-cell growth-stimulating factor
, thymic lymphoma cell-stimulating factor
, SDF-1 gamma
, Stromal cell-derived factor 1
, stromal cell-derived factor-1 gamma
, growth related gene 1
, growth-regulated protein homolog alpha
, C-X-C motif chemokine 12
, stromal-derived factor 1
, chemokine ligand 12b
, stromal cell derived factor 1
, stromal cell-derived factor-1 beta
, CXC chemokine
, CXCL12 chemokine
, growth regulated protein GRO
, chemokine ligand 12
, unm t30516