anti-Guanylate Cyclase Activator 1A (Retina) Antibodies
46 Guanylate Cyclase Activator 1A (Retina) (GUCA1A) Antibodies from 10 manufacturers are available on www.antibodies-online.com.
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anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) (AA 1-93) antibody Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) (C-Term) antibody Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) (AA 160-191), (C-Term) antibody Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) (AA 1-93) antibody Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) (N-Term) antibody Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) (AA 36-85) antibody Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) antibody Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) antibody Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) (AA 1-201) antibody Primary Antibody
anti-Guanylate Cyclase Activator 1A (Retina) (GUCA1A) antibody Primary Antibody
Guanylate Cyclase Activator 1A (Retina) (GUCA1A) Antigen Profile
Protein Summary
This gene plays a role in the recovery of retinal photoreceptors from photobleaching. In the recovery phase, the phototransduction messeneger cGMP is replenished by retinal guanylyl cyclase-1 (GC1). GC1 is activated by decreasing Ca(2+) concentrations following photobleaching. The protein encoded by this gene, guanylyl cyclase activating protein 1 (GCAP1), mediates the sensitivity of GC1 to Ca(2+) concentrations. GCAP1 promotes activity of GC1 at low Ca(2+) concentrations and inhibits GC1 activity at high Ca(2+) concentrations. Mutations in this gene cause autosomal dominant cone dystrophy (COD3)\; a disease characterized by reduced visual acuity associated with progressive loss of color vision. Mutations in this gene prohibit the inactivation of RetGC1 at high Ca(2+) concentrations\; causing the constitutive activation of RetGC1 and, presumably, increased cell death. This gene is expressed in retina and spermatagonia.
Alternative names and synonyms associated with Guanylate Cyclase Activator 1A (Retina) (GUCA1A)
- guanylate cyclase activator 1A (GUCA1A) antibody
- guanylate cyclase activator 1A (Guca1a) antibody
- guanylate cyclase activator 1A L homeolog (guca1a.L) antibody
- guanylate cyclase activator 1A (retina) (guca1a) antibody
- guanylate cyclase activator 1a (retina) (Guca1a) antibody
- guanylate cyclase activator 1A (guca1a) antibody
- C6orf131 antibody
- COD3 antibody
- CORD14 antibody
- dJ139D8.6 antibody
- GC-A antibody
- GCAP antibody
- gcap1 antibody
- GUCA antibody
- Guca1 antibody
- guca1a antibody
- MGC84170 antibody
- MGC146317 antibody
- mGCAP1 antibody
Protein level used designations for GUCA1A
GCAP 1 , cone dystrophy 3 , guanylate cyclase-activating protein, photoreceptor 1 , guanylin 1, retina , guanylyl cyclase-activating protein 1 , guanylate cyclase activator 1A (retina)
| GENE ID | SPECIES |
|---|---|
| 2978 | Homo sapiens |
| 282243 | Bos taurus |
| 301233 | Rattus norvegicus |
| 374216 | Gallus gallus |
| 444645 | Xenopus laevis |
| 609180 | Canis lupus familiaris |
| 748651 | Pan troglodytes |
| 779962 | Xenopus (Silurana) tropicalis |
| 100224057 | Taeniopygia guttata |
| 14913 | Mus musculus |
| 100715154 | Cavia porcellus |
| 140430 | Danio rerio |
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