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anti-Human BMP2 Antibodies:
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Human Polyclonal BMP2 Primary Antibody for IHC (p), ELISA - ABIN3043489
Tian, Sun, Zhang, Gao, Fu, Yang: Construction and expression of a bicistronic vector containing human bone morphogenetic protein 2 and vascular endothelial growth factor-165 genes in vitro. in Chinese medical journal 2009
Show all 14 Pubmed References
Human Polyclonal BMP2 Primary Antibody for IF (p), IHC (p) - ABIN730903
Huang, Zou, Shi, Zhang, Pen, Zhang, Gao, Wang: The effect of electroacupuncture on the extracellular matrix synthesis and degradation in a rabbit model of disc degeneration. in Evidence-based complementary and alternative medicine : eCAM 2014
Show all 9 Pubmed References
Human Polyclonal BMP2 Primary Antibody for IHC (p), IHC - ABIN446957
Yeom, Kim, Lee, Zhang, Lee, Hahm, Sohn, Lee: Effects of laser acupuncture on longitudinal bone growth in adolescent rats. in Evidence-based complementary and alternative medicine : eCAM 2013
Show all 8 Pubmed References
Human Monoclonal BMP2 Primary Antibody for ELISA - ABIN513751
Freire, You, Kook, Choi, Zadeh: Antibody-mediated osseous regeneration: a novel strategy for bioengineering bone by immobilized anti-bone morphogenetic protein-2 antibodies. in Tissue engineering. Part A 2011
Show all 6 Pubmed References
Human Polyclonal BMP2 Primary Antibody for IF, IHC (p) - ABIN2477681
Wendt, Homberg: Immunocytochemistry of dopamine in the brain of the locust Schistocerca gregaria. in The Journal of comparative neurology 1992
Show all 4 Pubmed References
Human Polyclonal BMP2 Primary Antibody for ELISA, WB - ABIN2477682
Kimura, Matsuo, Shibuya, Nakashima, Taga: BMP2-induced apoptosis is mediated by activation of the TAK1-p38 kinase pathway that is negatively regulated by Smad6. in The Journal of biological chemistry 2000
Show all 4 Pubmed References
Human Monoclonal BMP2 Primary Antibody for ELISA - ABIN513749
Duncan, Walters, Saldanha: Traumatized and inflamed--but resilient: glial aromatization and the avian brain. in Hormones and behavior 2013
Human Polyclonal BMP2 Primary Antibody for IHC, IHC (p) - ABIN4284882
Bridgewater, Mayo, Evanson, Whitt, Dean, Yates, Holden, Schmidt, Fox, Dhunghel, Steed, Adam, Nichols, Loganathan, Barrow, Hancock: A novel bone morphogenetic protein 2 mutant mouse, nBmp2NLS(tm), displays impaired intracellular Ca2+ handling in skeletal muscle. in BioMed research international 2013
In contrast to BMP-2, BMP-7 (show BMP7 Antibodies) concomitantly inhibited the expression of profibrotic genes
The binding free energies indicate that ALK-3 (show BMPR1A Antibodies) preferably binds to BMP-2 instead of BMP-9 (show GDF2 Antibodies). The structural analysis shows that ALK-3 (show BMPR1A Antibodies) binding with BMP-2 occurs in a perfectly symmetry pathway, whereas this symmetry is lost for possible ALK-3 (show BMPR1A Antibodies) interactions with BMP-9 (show GDF2 Antibodies)
The results demonstrate the efficacy of HPP (show SPTA1 Antibodies)-GC hydrogel in minimizing the diffusive loss of rhBMP-2 from the implantation site, compared to the collagen hydroxyapatite scaffold.
The in vitro results suggest that altered BMP2 regulatory function at rs1884302 may contribute to the etiology of sagittal nonsyndromic craniosynostosis. The in vivo results indicate that differences in regulatory activity depend on the presence of a C or T allele at rs1884302.
Collectively, according to our study, rhIL-6 could induce the extracellular calcification and osteogenic differentiation of human artery smooth muscle cells through upregulating endogenous BMP2 in vitro. This may be one of the underlying mechanisms of the overwhelming vascular calcification in rheumartoid arthritis.
HUCB-MSC (show MSC Antibodies) transfected with mTAT/PEI were shown to express more BMP-2 protein and mRNA.
These results showed that BMP2 activated SMAD1 (show GARS Antibodies)/5/8 phosphorylation and up-regulated BAMBI (show BAMBI Antibodies) mRNA in human granulosa-lutein cells.
BMP-2 can enhance HUVEC proliferation, migration and angiogenesis through P38, ERK and Akt/m-TOR pathway.
Study shows that recombinant human bone morphogenetic protein-2 activates hippo signaling through RASSF1 (show RASSF1 Antibodies) in esophageal cancer cells
SNPs in BMP2 can predict grade >/= 2 or 3 RP after radiotherapy for NSCLC and improve the predictive power of MLD (show ARSA Antibodies) model.
widespread myocardial Bmp2 and endocardial Notch (show NOTCH1 Antibodies) signaling drive presumptive ventricular endocardium to differentiate into valve endocardium
CTGF (show CTGF Antibodies) and BMP2 are induced following myocardial ischemia in mice and humans.
Results indicate that Notch (show NOTCH1 Antibodies) signaling induces cell cycle arrest and thereby initiates chondrocyte cell enlargement via bone morphogenetic protein 2 (BMP2) signaling.
Collectively, our findings indicate that CBFA2T2 (show CBFA2T2 Antibodies) is required for BMP-2-induced osteogenic differentiation of MSCs through inhibition of EHMT1 (show EHMT1 Antibodies)-mediated histone methylation at Runx2 (show RUNX2 Antibodies) promoter.
The data suggest that SDF-1beta provides synergistic effects supporting BMP-2-induced, BMSC-mediated bone formation and appears suitable for optimization of bone augmentation in combination therapy protocols.
study revealed that only BMP-6 (show BMP6 Antibodies) was able to induce bone formation at the used dose and that the addition of IGF-1 (show IGF1 Antibodies) contributed to an increase of the mineralization in the implants. Hence, the combination of BMP-6 (show BMP6 Antibodies) with IGF-1 (show IGF1 Antibodies) might be a better alternative than BMP-2 for orthopedic surgery or bone tissue engineering approaches.
BMP2 may induce osteogenic differentiation.
Increased bone mass in Crmp4 (show DPYSL3 Antibodies)(-/-) mice was associated with enhanced BMP2 signaling and BMP2-induced osteoblast differentiation in Crmp4 (show DPYSL3 Antibodies)(-/-) osteoblasts (OBs (show LEP Antibodies)).
Deletion of the "ultra-conserved sequence" within the 3'UTR of the Bmp2 was associated with elevated Bmp2 mRNA and BMP signaling levels, reduced fitness, and embryonic malformations.
Bone morphogenetic protein inhibition is sufficient for neural induction in vivo, and that in the absence of ventral BMPs, Spemann organizer signals are not required for brain formation.
Bmp antagonists and morpholinos designed against Bmp4, Bmp2, and Bmp7 demonstrate that Bmp signaling is critical for ventral, but not dorsoanterior endoderm formation
High BMP2 expression is associated with cystic ovarian disease.
both FSH (show BRD2 Antibodies) and BMP-2 reduced follicular mRNA expression of GDF9 (show GDF9 Antibodies) and NLRP5 (show NLRP5 Antibodies) when compared to follicles cultured in media containing only FSH (show BRD2 Antibodies)
The BMP2/4 (show BMP4 Antibodies) ligand and receptor system presides within bovine trophectoderm prior to uterine attachment.
concluded that a bone morphogenetic protein (BMP)-signaling system, consisting of BMP2, BMP4, type II and I receptors, is present in bovine antral follicles and plays a role in development and functioning of follicles rather than oocyte maturation
The transfecting capability of a BMP-2 specific vector is examined and supports the idea that BMP-2 might diminish osseointegration and implant fixation.
While BMP2 expression begins at (pregastrulation) stage 1 in the hypoblast, BMP4 (show BMP4 Antibodies) expression commences--distinctly delayed compared to the mouse--diffusely at (pregastrulation) stage 2; from stage 3 onwards.
Maxillary sinus floor elevation using BMP-2 gene-modified bone marrow stromal cells and TCP in rabbits
Data show that BMP-2, BMP-4 (show BMP4 Antibodies), and BMP-7 (show BMP7 Antibodies), noggin (show NOG Antibodies), and chordin (show CHRD Antibodies) were colocalized in rimming osteoblasts, osteoclasts, and chondrocytes.
BMP2 is not suitable to regenerate osteochondral lesions completely
High yield isolation of BMP-2 from bone and in vivo activity of a combination of BMP-2/TGF-beta1 (show TGFB1 Antibodies).
Report temporal regulation of BMP2 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.
Regional variation of periosteal activity at the mandibular ramus is regulated by differential induction of BMP2.
The effects of soy- and cow's milk-based formulas compared to nursing on bone development through BMP2 expression in neonatal pigs are reported.
The effect of bone morphogenetic protein (BMP) 12 and BMP2 expression on differentiation of bone marrow-derived mesenchymal stem cells and superficial digital flexor tenocytes is reported.
Study found that BMP-2 (show BMP4 Antibodies) is negatively regulated by miR (show MYLIP Antibodies)-140 during early embryogenesis and bone development in zebra fi sh.
Structures of Bmp2a, Bmp2b (show BMP4 Antibodies), Bmp4 (show BMP4 Antibodies) and Bmp16 were found to be remarkably similar; with residues involved in receptor binding being highly conserved.
bmp2a is a crucial player in the specification of the ventral pancreatic bud in zebrafish embryos.
results indicate that both the induction of a photoreceptor fate and the interaction with Notch (show NOTCH1 Antibodies) relies on a canonical BMP/Smad5 (show SMAD5 Antibodies) pathway
Mypt1 (show PPP1R12A Antibodies) mediates coordination between mesoderm and endoderm cell movements in order to carefully position the liver primordium such that it receives a Bmp2 (show BMP4 Antibodies) signal that is essential for liver formation
The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation.
, bone morphogenetic protein 2A
, bone morphogenetic protein 2 B
, bone morphogenetic protein 2-B
, bone morphogenetic protein 2
, Bone morphogenetic protein 2
, bone morphogenetic protein 2-like
, bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A)