Browse our anti-HSPA1A (HSPA1A) Antibodies

Zebrafish Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

1. Perturbation of the HSP70-HSP90 (show HSP90 Antibodies) heat-shock protein axis stimulates degradation of endothelial VEGFR2 (show KDR Antibodies).

2. HSP70, the earliest induced gene in the zebrafish retina after optic nerve injury, is a crucial factor for retinal ganglion cell survival and optic nerve regeneration.

3. HSP70 mRNA and protein were increased 2.2 fold at 0.5-24 hours after optic nerve injury then returned to control level.

4. hsp70 is required for embryonic lens development.

5. data suggest that HSF1 (show HSF1 Antibodies) is involved in regulating constitutive lens specific expression of hsp70 in the embryonic zebrafish.

6. in rheumatoid arthritis Significantly higher Hsp70 (heat shock protein 70 (show HSP70 Antibodies)) expression was found on synovial cells than on skin fibroblasts; high co-expression of CD91 (show LRP1 Antibodies) and Hsp70 on RA synovial cells

7. These results demonstrate that induction of Hsp70 in response to heat stress is dependent on ERK (show MAPK1 Antibodies) activation in Pac2 (show PSMG2 Antibodies) cells.

8. Hsp70 levels above the median were associated with a higher rate of progression to the accelerated/blast phase and a tendency toward shorter survival

Mouse (Murine) Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

1. HSPA1A and HSPA8 (show HSPA8 Antibodies) have roles in parturition through stimulating immune inflammatory and estrogen response

2. HSPA1A/B induction is a novel approach to delay thrombus formation with minimal bleeding risk in knockout mice.

3. HspA1A-phosphoinositide binding is complex yet specific, is mediated by both electrostatic and hydrophobic interactions, is not related to the lipid-head charge, and depends on the physicochemical properties of the lipid.

4. The protective mechanism of HAS2 (show HAS2 Antibodies) involves an increased expression of the heat-shock protein Hsp72, a chaperone with antiapoptotic activity

5. HspA1A embeds in membranes when bound to liposomes composed of cardiolipin and sulfatide.The two domains of HspA1A differentially bind to lipids, such as cardiolipin and sulfatide.

6. Knockdown lines were created for specific DSBs in regions of the chromosome that are coding for HSPA1A. Clonogenic cell survival was significantly lower in irradiated Hsp70 (show HSP70 Antibodies) KD cells with low mHsp70 expression, than in ctrl cells.

7. genetic manipulation of Hsp72 does not lead to alterations in metabolic processes in cardiac tissue under resting conditions, but identifies mouse strain-specific differences in cardiac lipid accumulation and insulin (show INS Antibodies)-stimulated glucose clearance.

8. Data indicate that heat shock protein 70 (Hsp70 (show HSP70 Antibodies)) is higher in nuclear protein 1 (Nupr1 (show NUPR1 Antibodies)+/-) haplodeficient mice, concomitant with improved insulin (show INS Antibodies) sensitivity.

9. HuR (show ELAVL1 Antibodies) does not play a role in APA (show ENPEP Antibodies) of the Hsp70.3 mRNA, and these two regulatory events appear to be mutually exclusive regulators of Hsp70.3 expression

10. Activating HSP72 in rodent skeletal muscle increases mitochondrial number and oxidative capacity and decreases insulin (show INS Antibodies) resistance.

Xenopus laevis Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

1. hsp72 was more potent than hsc73 (show HSPA8 Antibodies) in generating protective immune responses against the class Ia-negative 15/0 tumors.

Human Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

1. uHSP72 may be considered as a novel potential diagnostic biomarker for the early detection of Diabetic nephropathy (DN). Moreover, these data support the pivotal role of NLRP3 (show NLRP3 Antibodies) in the development and progression of DN

2. The G allele of rs1008438G>T of HSPA1A may be a protective factor for cervical cancer among ethnic Han Chinese from Yunnan.

3. measurable HSP72 was not associated with graft versus host disease following allogeneic hematopoietic cell transplantation

4. studies demonstrated that ovarian cancer cells isolated from patients with type II tumors released high levels of immunosuppressive cytokines (i.e., interleukin 10 (show IL10 Antibodies) and transforming growth factor beta) and HspA1A in vitro.

5. This study suggests that logotherapy affects the expression of cortisol, BDI, and pain scales in advanced cervical cancer patients, and that it does not affect the expression of HSP70 (show HSP70 Antibodies).

6. Data suggest that two putative NEF (nucleotide exchange factors) orthologs, GRPEL1 and GRPEL2 (show GRPEL2 Antibodies), modulate function of mitochondrial HSP70 (show HSP70 Antibodies) (mtHSP70 (show HSPA9 Antibodies)); both GRPEL1 and GRPEL2 (show GRPEL2 Antibodies) associate with mtHSP70 (show HSPA9 Antibodies) as hetero-oligomeric subcomplex and regulate mtHSP70 (show HSPA9 Antibodies) transport. (GRPEL = mitochondrial GrpE-like protein; HSP70 (show HSP70 Antibodies) = heat-shock protein 70 (show HSP70 Antibodies))

7. High HSP72 expression is associated with Cluster Amplified Centrosomes in cancer.

8. mRNA levels of HSP family members (HSP70B', HSP72, HSP40/DNAJ (show DNAJB1 Antibodies), and HSP20 (show HSPB6 Antibodies)/CRYAB (show CRYAB Antibodies)) are upregulated by the intracellular MMP3 (show MMP3 Antibodies) overload.

9. Data suggest that both ATP- and peptide-binding domains of HSPA1A can form complexes with an AU-rich element in VEGFA (show VEGFA Antibodies) mRNA in vitro; only peptide-binding domain can recover cellular VEGFA (show VEGFA Antibodies) mRNA in ribonucleoprotein immunoprecipitation; RNA-binding and mRNA-stabilizing functions of HSPA1A are independent of its protein chaperone cycle. (HSPA1A = heat shock 70 kDa protein 1A; VEGFA (show VEGFA Antibodies) = vascular endothelial growth factor A (show VEGFA Antibodies))

10. It has been demonstrated that HSPB8 (show HSPB8 Antibodies)-BAG3 (show BAG3 Antibodies)-HSP70 (show HSP70 Antibodies) ensures the functionality of stress granules and restores proteostasis by targeting defective ribosomal products for degradation.

Pig (Porcine) Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

1. overexpression of the HSP70.2 (show HSPA2 Antibodies) gene in multiple organs of transgenic mice improves survival during heatstroke by reducing hyperthermia, circulatory shock, and cerebral ischemia and damage

Cow (Bovine) Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

1. A new SNP in the 3'-UTR (show UTS2R Antibodies) of the hsp 70-1 (show HSP70 Antibodies) gene in Bos taurus and Bos indicus

2. The purified 44-kD ATPase domain from HSP70 exhibited intrinsic ATP-ADP exchange activity and acid-stable autophosphorylation at Thr204.

3. The effect of culture conditions on expression of heat shock protein 70 (show HSP70 Antibodies) and Bax (show BAX Antibodies) protein in bovine blastocysts is reported.

4. that HSC70 (show HSPA8 Antibodies) preconditioning (1) attenuates the TNF-alpha (show TNF Antibodies) response to endotoxin in macrophages in vitro, (2) induces cardiac functional tolerance to endotoxin and (3) reduces NF-kappaB (show NFKB1 Antibodies) activity, and TNF-alpha (show TNF Antibodies) and ICAM-1 (show ICAM1 Antibodies) levels in heart tissue.

5. the presence of SNPs (C/- and G/T) in the 5'-UTR (show UTS2R Antibodies) region of inducible Hsp70.1 ameliorates HS response and tolerance to heat of bovine peripheral blood mononuclear cells

6. This study showed that Hsp70 (show HSP70 Antibodies) concentration is a reliable indicator of chronic stress but is not a reliable indicator of a single stressor when animals are exposed to multiple chronic stressors.

7. Heat shock increased both HSP70 and IFNT expression in blastocysts.

8. the promoter region of bovine hsp70.1 gene is polymorphic and may be useful in selection of dairy cows for relatively better thermotolerance and higher milk production.

9. More DNMT1 (show DNMT1 Antibodies) mRNA was detected in the transgenic somatic cell nuclear transfer (SCNT) group than the other three groups. Hsp 70.1 mRNA was detected in the in vitro fertilzation embryos. Mash2 (show ASCL2 Antibodies) mRNA was present at highest levels in transgenic SCNT embryos.

10. In Sahiwal cattle the mRNA expression of HSP70 (show HSP70 Antibodies) and its protein concentration were higher (P<0.05) during peak summer (44 degrees C) and winter (10 degrees C) as compared to Frieswal cattle. This investigation supports the earlier information on the higher adaptability of indigenous cattle breeds to hot and humid conditions compared to the crossbreds of temperate cattle breeds.

Goat Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners