HSP70 1A antibody (AA 574-600)

Catalog No. ABIN659080

This Mouse Monoclonal antibody specifically detects HSP70 1A in WB and IF. It exhibits reactivity toward Human.

Quick Overview for HSP70 1A antibody (AA 574-600) (ABIN659080)

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSP70 1A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 201CT8-2-3

Product Details anti-HSP70 1A Antibody

Binding Specificity: AA 574-600

Predicted Reactivity: B, Pig

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This HSPA1A antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 574-600 amino acids from human HSPA1A.

Isotype: IgG1 kappa

Application Details

Application Notes: IF: 1:10~50. WB: 1:100~2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for HSP70 1A

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Alternative Name: HSPA1A

Background: This intronless gene encodes a 70 kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

Gene ID: 3304, 3303

NCBI Accession: NP_005336, NP_005337

UniProt: P08107

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process