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Trabecular meshwork cells express IL-20 receptors; Mutation of the T104 residue in IL-20R2 leads to a reduction in STAT3 phosphorylation as well as decreased matrix metalloproteinase activity
The crystal structure of the IL-20 (show IL20 ELISA Kits)/IL-20R1 (show IL20RA ELISA Kits)/IL-20R2 complex reveals how type I and II complexes discriminate cognate from noncognate ligands
crystallographic asymmetric unit contains one IL-20 (show IL20 ELISA Kits)-IL-20R1 (show IL20RA ELISA Kits)-IL-20R2 complex, corresponding to a solvent content of approximately 54%
Complete mda-7/IL-24 (show IL24 ELISA Kits) receptors (IL-22R1/IL-20R2 and IL-20R1 (show IL20RA ELISA Kits)/IL-20R2) are seldom expressed in liver cancer cell lines.
forms stable complex with interleukin-19 (show IL19 ELISA Kits) and interleukin-20 (show IL20 ELISA Kits) [IL-20R1 (show IL20RA ELISA Kits)][IL-20R2]
The hypotheses that genetic variations of the IL-20 (show IL20 ELISA Kits)-RI influence susceptibility to psoriasis and single nucleotide polymorphisms (SNPs) in the IL20RA (show IL20RA ELISA Kits) and IL20RB genes in psoriasis patients were investigated.
IL-20R1 (show IL20RA ELISA Kits) and IL-20R2 are constitutively express in the brain.
IL-20R2 receptor subunit is up-regulated by LPS (show TLR4 ELISA Kits) in the liver of normal mice.
IL-20R2 regulates T cell activation directly and attenuates antigen-specific CD8 (show CD8A ELISA Kits) responses; IL-20R2 signaling directly regulates CD8 (show CD8A ELISA Kits) and CD4 (show CD4 ELISA Kits) T cell responses in vitro and in vivo.
IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20 (IL20\; MIM 605619) (Blumberg et al., 2001
interleukin-20 receptor subunit beta
, interleukin 20 receptor beta
, IL-20 receptor subunit beta
, fibronectin type III domain containing 6
, interleukin-20 receptor II