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CBFB Proteins

(Core-Binding Factor, beta Subunit (CBFB))
The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit\; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus. In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain 11. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
CBFB Protein (AA 74-163) (GST tag) CBFB Protein (AA 74-163) (GST tag) CBFB Protein (AA 74-163) (GST tag) (ABIN1348166)

CBFB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

CBFB Protein (AA 1-182) (GST tag) CBFB Protein (AA 1-182) (GST tag) CBFB Protein (AA 1-182) (GST tag) (ABIN1348164)

CBFB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

CBFB Protein (AA 1-182) (His tag) (ABIN7417792)

CBFB Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC

CBFB Proteins by Origin

Find CBFB Proteins for a variety of species such as anti-Human CBFB, anti-Mouse CBFB. The species listed below are among those available. Click on a link to go to the corresponding products.

CBFB Proteins by Source

Here you will find CBFB Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CBFB Proteins by Protein Type

Here you can find CBFB Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

CBFB Proteins by Application

Find CBFB Proteins validated for a specific application such as WB, AP, AA, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular CBFB Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348166
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348164
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417792
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418203
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2713253
Quantity 20 μg
Datasheet Datasheet

Aliases for CBFB Proteins

core-binding factor beta subunit (CBFB) Proteins
core binding factor beta subunit (Cbfb) Proteins
core-binding factor, beta subunit (cbfb) Proteins
core-binding factor, beta subunit (Cbfb) Proteins
core-binding factor, beta subunit S homeolog (cbfb.S) Proteins
core binding factor beta (Cbfb) Proteins
core-binding factor beta subunit (Cbfb) Proteins
AI893578 Proteins
cbf-beta Proteins
Cbfb Proteins
CBFB Proteins
cbfbeta Proteins
PEA2 Proteins
pea2-beta Proteins
Pebp2 Proteins
pebp2-beta Proteins
PEBP2B Proteins
pebp2b Proteins
PEBP2b Proteins
Pebpb2 Proteins
unp1266 Proteins
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