anti-Immunoglobulin E (IgE) secondary antibodies

is only found in mammals. is the least abundant isotype of all antibodies, but it is capable of triggering the most powerful immune reactions. plays an important role in allergy, and leads to excessive activation of mast cells and basophils by binding to their Fc receptors, resulting in an extreme inflammatory response.

Except its established function for allergy, there is still speculation about the physiological contributions of . In animal models circumstantial evidence hints to IgE fighting gut parasites like parasitic worms, but this has not been conclusively proven in humans. may play some role in the immune system?s recognition of cancer. However, so far there is only circumstantial evidence for this hypothesis though, like for example the observation that the prevalence of several cancers is lower in individuals with allergies. Additionally, treatment with immunesystem-suppressing substances increases the cancer risk. Interestingly, individuals with allergies have lower level of toxins. It is thought possible, that bind an help to destroy or excrete toxins.

Below you will find a list of anti- secondary antibodies.