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Julian Pampel

Julian Pampel, BSc

Content Manager at antibodies-online.com
Alumni of: Leibniz Universität Hannover

Creative mind of antibodies-online with a keen eye for details. Proficient in the field of life-science with a passion for plant biotechnology and clinical study design. Responsible for illustrated and written content at antibodies-online as well as supervision of the antibodies-online scholarship program.

Articles by Julian Pampel

anti-Immunoglobulin G (IgG) secondary antibodies

Each IgG is composed of four peptide chains - two class γ heavy chains of about 50 kDa and two light chains of about 25 kDa - with two antigen binding sites. Hence, IgG antibodies are large molecules of about 150 kDa. Read more

anti-Immunoglobulin A (IgA) secondary antibodies

Immunoglobulin A plays a role in mucosal immunity and is produced in mucosal linings. Hence IgA can be found in mucous secretions, including tears, saliva, colostrum, secretions from the gastrointestinal tract, and others, but it is found only in small amounts in blood. Read more

anti-Immunoglobulin E (IgE) secondary antibodies

IgE is only found in mammals. IgE is the least abundant isotype of all antibodies, but it is capable of triggering the most powerful immune reactions. IgE plays an important role in allergy, and leads to excessive activation of mast cells and basophils by binding to their Fc receptors, resulting in an extreme inflammatory response. Read more

anti-Immunoglobulin M (IgM) secondary antibodies

IgM is constructed of five or six units (i.e. mostly as pentamers but also hexamers occur) which are each comprised of two heavy-chains (mu-chains) and two light chains, bound together by disulfide bonds and a so-called J-chain. Read more

anti-Immunoglobulin Y (IgY) secondary antibodies

Immunoglobulin Y (IgY) is found in birds, and it is being isolated for biotechnological applications from egg-yolk of chicken eggs. Studies have suggested that Immunoglobulin Y is functionally similar to IgG, and also shares some similarity with IgE. Read more

Peptide Synthesis - Methods and Reagents

In organic chemistry, peptide synthesis is the production of peptides, in which multiple amino acids are linked via peptide bonds. In contrast the biological process of producing long peptides (proteins) is usually referred to as protein biosynthesis. Read more

Magnetic Beads

Magnetic beads are an ideal tool for immobilizing molecules like proteins (enzymes, antibodies, peptides etc.) or nucleic acids on a solid phase; they can be further used in various applications. Read more

Products for Plant-specific Targets

Modern molecular biology has opened up a whole new range of techniques and possibilities to scientists working in the different fields of the classical plant sciences like plant physiology, breeding or pathology. Read more

Protein Labels

Biological research often requires the use of molecular labels that are covalently attached to a protein of interest to facilitate detection or purification of the labeled protein and/or its binding partners. Read more

Protein Expression Systems

Comparison of Recombinant Protein Expression Systems: Advantages and downfalls of E.coli, Yeast, CHO and plant cells in recombinant protein production. Discover high quality proteins from antibodies-online. Read more

Model Organisms

When researchers look for an organism to use in their studies, they look for several traits. Among these are size, generation time, accessibility, manipulation, genetics, conservation of mechanisms, and potential economic benefit. Read more

Chromatin immunoprecipitation (ChIP)

Immunoprecipitation of protein-DNA complexes (ChIP) enables the study of epigenetic relations. The technique identifies binding sites of DNA-associated proteins and allows a closer study of transcription factors. Read more

CUT&RUN - Improved Method to Study Protein-DNA Interactions

CUT&RUN-sequencing, also known as Cleavage Under Targets and Release Using Nuclease, is a method used to analyze protein interactions with DNA. CUT&RUN-sequencing combines  antibody-targeted controlled cleavage by micrococcal nuclease with massively parallel DNA sequencing to identify the binding sites of DNA-associated proteins. Read more

SARS-CoV-2 Life Cycle: Stages and Inhibition Targets

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) belongs to the enveloped positive-sense RNA viruses. This virus is characterized by club-like spikes on the surface, and a unique replication strategy. Cell entry of coronaviruses depends on binding of the viral spike (S) proteins to cellular receptors and on S protein priming by host cell proteases. Unravelling which cellular factors are used by SARS-CoV-2 for entry might provide insights into viral transmission and reveal therapeutic targets. Read more

antibodies-online CUT&RUN and CUT&Tag Handbook

antibodies-online CUT&RUN and CUT&Tag Handbook Read more

GFP Catcher - High-Affinity Single-Domain Antibodies

antibodies-online offers catchers for / ideal tool. Our current product lines are based on recombinant single-domain antibodies (sdAbs) derived from llamas or alpacas. This type of affinity molecules (also known as “Nanobodies”; trademark owned by Ablynx) provide significant advantages over conventional IgG molecules. All of our products are produced in-house. They are highly specific with affinities tailored for a wide range of applications. Read more

CUT&RUN Combo: Beads, Controls, Primary, MNase in One go!

CUT&RUN stands for "Cleavage Under Targets and Release Using Nuclease". CUT&RUN introduces some major modifications to eliminate shortcomings inherent to ChIP-seq. Benefit from our customizable CUT&RUN Combo : Choose from validated Beads, a wide collection of primary Antibodies, Controls, and pAG-MNase Read more

anti-Immunoglobulin D (IgD) Secondary Antibodies

IgD (IgD) is a monomeric antibody isotype that is expressed in the plasma membranes of immature B-lymphocytes. IgD is also produced in a secreted form that is found in small amounts in blood serum. Secreted IgD is made up of two heavy chains of the delta class, and two light chains. IgD's function has long been a conundrum and is still incompletely understood. IgD is present in species ranging from fish to human (probably with the exception of birds), indicating that IgD has been preserved since its ancient origins which suggests that IgD has important immunological functions. Read more

Hallmarks of Cancer Handbook

Download our Hallmarks of Cancer Handbook Read more

Neurodegenerative Diseases

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Huntington's Disease

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SARS-CoV-2 Proteins

antibodies-online has served hundreds of research institutions around the world with SARS-CoV-2 Proteins and SARS-CoV-2 Recombinant Proteins. If you are looking for the right SARS-CoV-2 Protein to suit your research setting, for Immunizations, for Kit Dev Read more

SARS-CoV-2 / COVID-19 ELISA Kits

antibodies-online has served hundreds of research institutions around the world with SARS-CoV-2 ELISA Kits. If you are looking for the right SARS-CoV-2 ELISA Kit to suit your research setting, we have grouped our current SARS-CoV-2 ELISA Kit catalogue by Read more

Protein Tags

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Hallmarks of Cancer

Hallmarks of Cancer Read more

Epigenetics

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Histone H3 Antibodies

Histone H3 Antibodies Read more

Histone H4 Antibodies

Histone H4 Antibodies Read more

Transcription Factors

Transcription Factors Read more

CUT&Tag

CUT&Tag Read more

DNA Modification

DNA Modification Read more

Chromatin Remodeling

Chromatin Remodeling Read more

Immuno-Oncology

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Cytokeratins in Tumor Detection

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Host Cell Proteins

Host Cell Proteins Read more

Lateral Flow Antibodies

Lateral Flow Antibodies Read more

RNA Based Therapeutics

RNA Based Therapeutics - Drug Discovery Read more

Spatial Biology

Spatial Biology Read more

Biosimilar Antibodies

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The Role of Fc Receptor Neonatal in Cancer

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