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Human Polyclonal FNTA Primary Antibody for IHC (p), WB - ABIN1882083
Wang, Danielson, Li, Shah, Kim, Donahoe: The p21(RAS) farnesyltransferase alpha subunit in TGF-beta and activin signaling. in Science (New York, N.Y.) 1996
Show all 5 Pubmed References
Exploring the putative self-binding property of the human farnesyltransferase alpha-subunit (show POLG Antibodies)
Geranylgeranyltransferase inhibitor-2147 (GGTI (show PGGT1B Antibodies)-2147), an inhibitor of protein prenylation, elicited significant inhibition of glucose-stimulated insulin (show INS Antibodies) secretion from INS (show INS Antibodies) 832/13 islet cells.
FTase, via its tubulin (show TUBB Antibodies)-association, is a critical upstream regulator of HDAC6 (show HDAC6 Antibodies) activity
Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13.
, farnesyl-protein transferase alpha-subunit
, protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
, protein prenyltransferase alpha subunit repeat containing 2
, ras proteins prenyltransferase subunit alpha
, type I protein geranyl-geranyltransferase alpha subunit
, CAAX farnesyltransferase subunit alpha
, type I protein geranyl-geranyltransferase subunit alpha
, Farnesyltransferase, subunit alpha