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Browse our anti-Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1) Antibodies

Full name:: anti-Elongation Factor Tu GTP Binding Domain Containing 1 Antibodies (EFTUD1)

On www.antibodies-online.com are 26 Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1) Antibodies from 10 different suppliers available. Additionally we are shipping Elongation Factor Tu GTP Binding Domain Containing 1 Kits (3) and many more products for this protein. A total of 32 Elongation Factor Tu GTP Binding Domain Containing 1 products are currently listed.

Synonyms:: 4932434J20Rik, 6030468D11Rik, AI451340, AU019507, AU022896, D7Ertd791e, FAM42A, HsT19294, RIA1

list all antibodies	Gene Name	GeneID	UniProt
	EFTUD1	79631	Q7Z2Z2
	EFTUD1	101592	Q8C0D5
	EFTUD1
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Most Popular Reactivities for anti-Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1) Antibodies

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anti-Human Antibodies:

anti-Mouse (Murine) Antibodies:

16 WB Antibodies

anti-Rat (Rattus) Antibodies:

4 WB Antibodies

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More product categories related to Elongation Factor Tu GTP Binding Domain Containing 1 Antibody

More Antibodies against Elongation Factor Tu GTP Binding Domain Containing 1 Interaction Partners

Human Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1) interaction partners

the effect of SBDS mutations on the interaction with EFL1were tested, and showed that all tested mutations disrupted the binding to EFL1.
Mutations in EFL1 clinically manifest phenotypes of infantile pancytopenia, exocrine pancreatic insufficiency and skeletal anomalies. Mutant EFL1 proteins do not promote the release of yeast cytoplasmic Tif6 from the 60S subunit, likely preventing the formation of mature ribosomes.
Association of Elongation Factor-like 1 (EFL1) GTPase to SBDS did not modify the affinity for GTP but dramatically decreased that for GDP by increasing the dissociation rate of the nucleotide.
Upon EFL1 binding, SBDS is repositioned around helix 69, thus facilitating a conformational switch in EFL1 that displaces eIF6 by competing for an overlapping binding site on the 60S ribosomal subunit.
Downregulation of EFTUD1 induced cell-cycle arrest and apoptosis in gliomas by impairing ribosome biogenesis

Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1) Antigen Profile

Antigen Summary

Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.

Alternative names and synonyms associated with Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1)

elongation factor like GTPase 1 (EFL1) antibody
elongation factor like GPTase 1 (Efl1) antibody

4932434J20Rik antibody
6030468D11Rik antibody
AI451340 antibody
AU019507 antibody
AU022896 antibody
D7Ertd791e antibody
FAM42A antibody
HsT19294 antibody
RIA1 antibody

Protein level used designations for EFTUD1

elongation factor Tu GTP-binding domain-containing protein 1 , elongation factor-like 1 , ribosome assembly 1 homolog

GENE ID	SPECIES
79631	Homo sapiens
101592	Mus musculus

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