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EFTUD1 antibody (C-Term)

EFTUD1 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2774502
  • Target See all EFTUD1 Antibodies
    EFTUD1 (Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1))
    Binding Specificity
    • 8
    • 8
    • 7
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
    Host
    • 19
    Rabbit
    Clonality
    • 19
    Polyclonal
    Conjugate
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    This EFTUD1 antibody is un-conjugated
    Application
    • 18
    • 14
    • 13
    • 13
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    TTEEEYLHFG EKADSENQAR KYMNAVRKRK GLYVEEKIVE HAEKQRTLSK
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    Characteristics
    This is a rabbit polyclonal antibody against EFTUD1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human EFTUD1
    Top Product
    Discover our top product EFTUD1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1069 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    EFTUD1 (Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1))
    Alternative Name
    EFTUD1 (EFTUD1 Products)
    Synonyms
    FAM42A antibody, HsT19294 antibody, RIA1 antibody, 4932434J20Rik antibody, 6030468D11Rik antibody, AI451340 antibody, AU019507 antibody, AU022896 antibody, D7Ertd791e antibody, elongation factor like GTPase 1 antibody, elongation factor like GPTase 1 antibody, EFL1 antibody, Efl1 antibody
    Background
    EFTUD1 is involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, EFTUD1 triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. EFTUD1 has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.
    Alias Symbols: FAM42A, HsT19294, RIA1
    Protein Interaction Partner: TP53RK, FKBP10, RPRD1B, OSGEP, PANK4, NSUN2, UFM1, KIAA1279, ACTR2, TPD52L2, RANGAP1, LPP, BAG1, UBC,
    Protein Size: 1069
    Molecular Weight
    117 kDa
    Gene ID
    79631
    NCBI Accession
    NM_001040610, NP_001035700
    Pathways
    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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