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anti-Human SNRPB2 Antibodies:
anti-Mouse (Murine) SNRPB2 Antibodies:
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Our study provides new insights into how RBPs, and specifically SNRPB (show SNRPB Antibodies), regulate gene expression and directly impact GBM development.
These results confirm the specificity of SNRPB (show SNRPB Antibodies) mutations in CCMS and provide further evidence for the role of spliceosomal proteins in craniofacial and thoracic development.
Mutations in the regulatory alternative exon of SNRPB (show SNRPB Antibodies) disrupted it's auto-regulation and caused cerebro-costo-mandibular syndrome.
Cerebro-costo-mandibular syndrome is due to heterozygous mutations in SNRPB (show SNRPB Antibodies).
Highly mobile SmB protein-trafficking vesicles in neural cells are dependent on the cellular levels of SMN and SmB for their morphology and mobility.
Data suggest that protein-protein interactions localize U2A' (SNRPA1 (show SNRPA Antibodies)) to the U2 snRNP (show LSM2 Antibodies) (U2 small nuclear ribonucleoprotein) and exclude it from the U1 snRNP (show LSM2 Antibodies), rather than to enhance U2 snRNA (U2 small nuclear RNA; RNU2-1) binding of U2B'' (SNRPB2).
in addition to affecting coilin-coilin (show COIL Antibodies) interaction and localization in the nucleus, the phosphorylation state of coilin (show COIL Antibodies) also impacts its interaction with SMN (show STMN1 Antibodies) and SmB' and may play a role in controlling U snRNP (show LSM2 Antibodies) cycling through the Cajal bodies.
The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.
U2 small nuclear ribonucleoprotein B''
, U2 snRNP B''
, small nuclear ribonucleoprotein polypeptide B2
, U2 small nuclear ribonucleoprotein B
, B polypeptide of Sm protein
, Sm protein B/B'
, small nuclear ribonucleoprotein polypeptide B
, small nuclear ribonucleoprotein polypeptides B and B'
, small nuclear ribonucleoprotein-associated proteins B and B'
, small nuclear ribonucleoprotein polypeptide B L homeolog