Browse our anti-Lactate Dehydrogenase C (LDHC) Antibodies

Cow (Bovine) Lactate Dehydrogenase C (LDHC) interaction partners

1. Hyaluronic acid induces sperm capacitation involving lactate dehydrogenase (LDH) and creatine kinase (CK) activities, thereby reducing oxidative metabolism, and this process is mediated by mAC.

Human Lactate Dehydrogenase C (LDHC) interaction partners

1. a novel association between the methylation status of CpG sites within LDHC and the development of insulin autoantibodies in the first years of life

2. Lactate dehydrogenase C may act as a novel biomarker for renal cell carcinoma progression and a potential therapeutic target for the treatment of renal cell carcinoma.

3. three uniquely identified proteins (CDK6 , galectin-3-binding protein and LDH C) were found, which show tight connection with prostate cancer and presence of all of them was previously linked to certain aspects of prostate cancer

4. Down-regulated LDH-C4 expression is significantly correlated with lowered enzyme activity in human spermatozoa.

5. This is the first report to show a positive correlation between LDH-3 and hemolytic parameters in sickle cell anemia.

6. Results show that S-100B, MIA and LDH levels were significantly higher in patients with advanced melanoma than in disease-free patients or healthy controls.

7. Elevated serum LDH isoenzymes and AST indicate a disturbance (of uncertain clinical significance) within multiple extraosseous tissues when there is CLCN7 deficiency.

8. LDH3 was increased in essential thrombocythemia. This isoenzymatic pattern could be expression of a metabolic adaptation.

9. LDH3 is a supporting diagnostic marker in cases of chronic tuberculosis.

10. hLdhc expression in cancer cells was regulated by transcription factor Sp1 and CREB and promoter CGI methylation

Mouse (Murine) Lactate Dehydrogenase C (LDHC) interaction partners

1. the LDHA protein level was remarkably decreased in Ldhc-deficient sperm, indicating that LDHC is required for LDHA expression in the sperm.

2. polymorphisms in the Ldhc gene control testis levels of S-2HG, and thereby epigenetics, across mammals

3. Human LDHA was introduced as a transgene to Ldhc-null mice and rescued sperm function.

4. C57BL/6 and 129S6 Ldhc KO mice were subfertile and infertile respectively.

5. part of a complex involved in ATP homeostasis in sperm

6. required for sperm to accomplish fertilization

7. The high level of LDH-C(4) in postmeiotic cells results from mRNA and protein stability.

8. Excess oxidative stress in selenium deficient mice affects the spermatogenic process with a reduction in mature sperm and in turn the LDH-X level.

9. Ldh3 mRNA is transcribed in oocytes and cannot be detected in fertilized eggs. Ldh3 protein, however, persists to the blastocyst stage of embryonic development localizing mainly to the cortex region of oocytes, eggs, zygotes, and embryonic blastomeres.

10. beta-agonists increased serum LDH levels, but it was not due to release from the heart.

11. Simultaneous occupancy of the GC box and CRE sites in the core promoter is necessary for full expression of Ldhc in the testis.

12. LDHC plays an essential role in maintenance of the processes of glycolysis and ATP production in the flagellum that are required for male fertility and sperm function.