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anti-Human Lactate Dehydrogenase C Antibodies:
anti-Mouse (Murine) Lactate Dehydrogenase C Antibodies:
anti-Rat (Rattus) Lactate Dehydrogenase C Antibodies:
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Human Polyclonal Lactate Dehydrogenase C Primary Antibody for IP, WB - ABIN517463
Lo, Jamsai, OConnor, Borg, Clark, Whisstock, Field, Adams, Ishikawa, Aitken, Whittle, Goodnow, Ormandy, OBryan: RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. in PLoS genetics 2012
Human Polyclonal Lactate Dehydrogenase C Primary Antibody for IHC (p), ELISA - ABIN548145
Mazzotta, Guerranti, Gozzetti, Bucalossi, Bocchia, Sammassimo, Petralia, Ogueli, Lauria: Increased serum lactate dehydrogenase isoenzymes in Ph-negative chronic myeloproliferative diseases: a metabolic adaptation? in Hematology (Amsterdam, Netherlands) 2006
Hyaluronic acid induces sperm capacitation involving lactate dehydrogenase (LDH) and creatine kinase (CK) activities, thereby reducing oxidative metabolism, and this process is mediated by mAC.
a novel association between the methylation status of CpG sites within LDHC and the development of insulin autoantibodies in the first years of life
Lactate dehydrogenase C may act as a novel biomarker for renal cell carcinoma progression and a potential therapeutic target for the treatment of renal cell carcinoma.
three uniquely identified proteins (CDK6 , galectin-3-binding protein and LDH C) were found, which show tight connection with prostate cancer and presence of all of them was previously linked to certain aspects of prostate cancer
Down-regulated LDH-C4 expression is significantly correlated with lowered enzyme activity in human spermatozoa.
This is the first report to show a positive correlation between LDH-3 and hemolytic parameters in sickle cell anemia.
Results show that S-100B, MIA and LDH levels were significantly higher in patients with advanced melanoma than in disease-free patients or healthy controls.
Elevated serum LDH isoenzymes and AST indicate a disturbance (of uncertain clinical significance) within multiple extraosseous tissues when there is CLCN7 deficiency.
LDH3 was increased in essential thrombocythemia. This isoenzymatic pattern could be expression of a metabolic adaptation.
LDH3 is a supporting diagnostic marker in cases of chronic tuberculosis.
hLdhc expression in cancer cells was regulated by transcription factor Sp1 and CREB and promoter CGI methylation
the LDHA protein level was remarkably decreased in Ldhc-deficient sperm, indicating that LDHC is required for LDHA expression in the sperm.
polymorphisms in the Ldhc gene control testis levels of S-2HG, and thereby epigenetics, across mammals
Human LDHA was introduced as a transgene to Ldhc-null mice and rescued sperm function.
C57BL/6 and 129S6 Ldhc KO mice were subfertile and infertile respectively.
part of a complex involved in ATP homeostasis in sperm
required for sperm to accomplish fertilization
The high level of LDH-C(4) in postmeiotic cells results from mRNA and protein stability.
Excess oxidative stress in selenium deficient mice affects the spermatogenic process with a reduction in mature sperm and in turn the LDH-X level.
Ldh3 mRNA is transcribed in oocytes and cannot be detected in fertilized eggs. Ldh3 protein, however, persists to the blastocyst stage of embryonic development localizing mainly to the cortex region of oocytes, eggs, zygotes, and embryonic blastomeres.
beta-agonists increased serum LDH levels, but it was not due to release from the heart.
Simultaneous occupancy of the GC box and CRE sites in the core promoter is necessary for full expression of Ldhc in the testis.
LDHC plays an essential role in maintenance of the processes of glycolysis and ATP production in the flagellum that are required for male fertility and sperm function.
Lactate dehydrogenase C catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHC is testis-specific and belongs to the lactate dehydrogenase family. Two transcript variants have been detected which differ in the 5' untranslated region.
lactate dehydrogenase C
, L-lactate dehydrogenase C
, L-lactate dehydrogenase C chain
, LDH testis subunit
, cancer/testis antigen 32
, lactate dehydrogenase C4
, lactate dehydrogenase c variant 1
, lactate dehydrogenase c variant 3
, lactate dehydrogenase c variant 4
, lactate dehydrogenase 3, C chain, sperm specific
, lactate dehydrogenase-X
, lactate dehydrogenase C variant 3
, lactate dehydrogenase-C