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This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of this gene is located on the long arm of chromosome X.
, tRNA-guanine transglycosylase
, Guanine insertion enzyme
, queuine tRNA-ribosyltransferase
, guanine insertion enzyme
, TGT, 43-KD subunit
, TGT, catalytic subunit
, queuine tRNA-ribosyltransferase 1 (tRNA-guanine transglycosylase)