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Human EPGN Protein expressed in Escherichia coli (E. coli) - ABIN1686210
Tai, Bilousova, Jungbauer, Roeske, Youmans, Yu, Poon, Cornwell, Miller, Vinters, Van Eldik, Fardo, Estus, Bu, Gylys, Ladu: Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples. in The Journal of biological chemistry 2013
The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate. Alternative splicing results in multiple transcript variants.
, epithelial mitogen homolog