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anti-Mouse (Murine) Ephrin B2 Antibodies:
anti-Rat (Rattus) Ephrin B2 Antibodies:
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Human Polyclonal Ephrin B2 Primary Antibody for CyTOF, FACS - ABIN4900008
Zhang, Dong, Wang, Zhu, Croy: Dynamic changes occur in patterns of endometrial EFNB2/EPHB4 expression during the period of spiral arterial modification in mice. in Biology of reproduction 2008
Show all 16 Pubmed References
Human Polyclonal Ephrin B2 Primary Antibody for IHC - ABIN966079
Chrencik, Brooun, Kraus, Recht, Kolatkar, Han, Seifert, Widmer, Auer, Kuhn: Structural and biophysical characterization of the EphB4*ephrinB2 protein-protein interaction and receptor specificity. in The Journal of biological chemistry 2006
Show all 3 Pubmed References
Human Polyclonal Ephrin B2 Primary Antibody for IHC, IHC (p) - ABIN4308730
Nakayama, Nakayama, van Lessen, Yamamoto, Hoffmann, Drexler, Itoh, Hirose, Breier, Vestweber, Cooper, Ohno, Kaibuchi, Adams: Spatial regulation of VEGF receptor endocytosis in angiogenesis. in Nature cell biology 2013
Show all 3 Pubmed References
Human Polyclonal Ephrin B2 Primary Antibody for IHC - ABIN966078
Noren, Lu, Freeman, Koolpe, Pasquale: Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth. in Proceedings of the National Academy of Sciences of the United States of America 2004
Show all 2 Pubmed References
Human Polyclonal Ephrin B2 Primary Antibody for ELISA, WB - ABIN4308729
Nakada, Anderson, Demuth, Nakada, Reavie, Drake, Hoelzinger, Berens: The phosphorylation of ephrin-B2 ligand promotes glioma cell migration and invasion. in International journal of cancer 2010
Show all 2 Pubmed References
Human Polyclonal Ephrin B2 Primary Antibody for IF, WB - ABIN362834
Kertesz, Krasnoperov, Reddy, Leshanski, Kumar, Zozulya, Gill: The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth. in Blood 2006
Show all 4 Pubmed References
It functioned by interrupting the phosphorylation of EphrinB2 and its related signaling pathway.
EphrinB2 affects apical constriction in Xenopus embryos and is regulated by ADAM10 (show ADAM10 Antibodies) and flotillin-1 (show FLOT1 Antibodies).
Results show that EfnB2 plays a previously unrecognized role as a principal regulator of hematopoiesis from the dorsal aorta and embryonic stem cells by controlling the emergence of hemogenic endothelial cells. During vascular development, EfnB2 is essential for the proper sorting of arterial and venous-fated endothelium into distinct arterial and venous vascular beds.
Data reveal that ephrinB2 and ephrinB3 signaling is required to control progenitor identities in the ventral spinal cord.
that expression of EFNB1 (show EFNB1 Antibodies) and EFNB2 is implicated in Th cell differentiation and migration to inflammatory sites in both EAE and MS
As endothelial progenitor cells (EPCs)derived from mouse bone marrow were cultured on substrates of increasing stiffness, the mRNA and protein levels of the specific arterial endothelial cell marker ephrinB2 were found to increase, while the expression of the venous marker EphB4 (show EPHB4 Antibodies) decreased
an autonomous receptor-like role for ephrin-B reverse signaling in the tangential migration of interneurons into the neocortex using ephrin-B (EfnB1 (show EFNB1 Antibodies)/B2/B3) conditional triple mutant (TM(lz)) mice, is reported.
During urogenital development, different modes of Eph (show EPHA1 Antibodies)/Ephrin signaling occur at several sites with EphrinB2 and EphrinA5 acting in concert.
Male Efnb2 knockout mice presented reduced blood pressure. Region from aa 313 to aa 331 of EFNB2 was essential for reverse signaling regulating VSMC contractility.
Suggest role for ephrinB2/EphB4 (show EPHB4 Antibodies) signaling in the maintenance of neurovascular homeostasis and show that EphrinB2 activation promotes vascular repair mechanisms and reduces brain swelling after mild cerebral ischemia.
The Eph (show EPHA1 Antibodies)/ephrin-B2-mediated heterotypic or homotypic cell interactions between thymocytes and thymic epithelial cells (TECs), or between TECs and themselves, contribute to the early maturation of MTS20(+) TECs.
Control of abscission requires Eph (show EPHA1 Antibodies) kinase activity, and Src (show SRC Antibodies) and citron kinase (show CIT Antibodies) (CitK) are downstream effectors in the Eph (show EPHA1 Antibodies)-induced signal transduction cascade
This is the novel report describing to demonstrate that the Runx2 (show RUNX2 Antibodies) expression of MSC (show MSC Antibodies) is synergistically influenced by the hydrogels elasticity and their manner of ephrinB2 immobilized.
the binding of the viral attachment protein G to its host receptor ephrinB2 was studied and showed monomeric and dimeric receptors activate distinct conformational changes in G.
results suggest that ephrin-B2 overexpression and activation of the ephrin-B2 reverse signaling pathway in tumor microenvironment in OSCC facilitates progression and lymph node metastasis via enhancement of malignant potential and interaction with surrounding cells
Proteomic analysis of their secretome reveals a signature, including ephrin-B2, that predicts decreased survival of glioma patients. We find that ephrin-B2 is an important pro-angiogenic tenascin-C (show TNC Antibodies) effector.
In human glioblastoma stem-like cells-derived orthotopic xenografts, EFNB2 knock-down blocked tumour initiation and treatment of established tumours with ephrin-B2-blocking antibodies suppressed progression.
High EFNB2 expression is associated with preeclampsia.
Inhibition of EphB4 (show EPHB4 Antibodies) forward signaling using soluble EphB4 (show EPHB4 Antibodies) protein fused (show AXIN1 Antibodies) with murine serum albumin (show ALB Antibodies) failed to affect eRMS model tumor progression, but did moderately slow progression in murine aRMS
Study shows that EFNB2 is overexpressed in head and neck squamous cell carcinoma, pancreatic adenocarcinoma, and urothelial bladder carcinoma, and its overexpression correlates with poor survival of the cancer patients.
Five SNPs in the 3' region of the EFNB2 were in linkage disequilibrium and significantly associated with hypertension for male but not female subjects.
The porcine EFNB2 gene was characterized and cloned. The porcine EFNB2 gene was expressed in ten different tissues from 25-day-old Shaziling and Yorkshire piglets, with the highest expression observed in the longissimus dorsi.
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.
, ephrin-B2 precursor
, ephrin B2
, EPH-related receptor tyrosine kinase ligand 5
, HTK ligand
, eph-related receptor tyrosine kinase ligand 5
, ligand of eph-related kinase 5