FGFR4 ELISA Kits

Protein Summary

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.

Alternative names and synonyms associated with FGFR4

• fibroblast growth factor receptor 4 (FGFR4) antibody
• fibroblast growth factor receptor 4 (fgfr4) antibody
• fibroblast growth factor receptor 4 (Fgfr4) antibody
• fibroblast growth factor receptor 4 S homeolog (fgfr4.S) antibody

• CD334 antibody
• etID309818.21 antibody
• Fgfr-4 antibody
• fgfr-4c antibody
• fgfr4 antibody
• Show all synonym aliases
• JTK2 antibody
• TKF antibody
• wu:fc13h10 antibody
• XFGFR-4 antibody
• XFGFR-4a antibody
• xfgfr4 antibody
• zgc:111935 antibody

Protein level used designations for FGFR4

fibroblast growth factor receptor 4 , FGF receptor 4 , FGFR-4 , hydroxyaryl-protein kinase , protein-tyrosine kinase , tyrosine kinase related to fibroblast growth factor receptor , tyrosylprotein kinase , CTLA-2-beta protein , fibroblast growth factor receptor 4 16 minus form , protein-tyrosine kinase receptor MPK-11 , fibroblast growth factor receptor FREK , fibroblast growth factor receptor-like embryonic kinase , fibroblast growth factor receptor 4c