Browse our anti-VEGFB (VEGFB) Antibodies

Human Vascular Endothelial Growth Factor B (VEGFB) interaction partners

1. High plasma VEGF-B levels are associated with type 2 diabetes mellitus.

2. Data from clinical studies point out the changes in circulating or tissue expression levels of VEGF-B in obese compared with lean patients.

3. Cardiac transgenic vascular endothelial growth factor-B overexpression failed to protect heart transplants from ischemia-reperfusion injury.

4. renal VEGF-B expression correlates with the severity of Diabetic Kidney Disease.

5. Data show that metformin treatment reduces serum vascular endothelial growth factor B (VEGF-B) levels and ameliorates insulin (show INS Antibodies) resistance.

6. VEGFA (show VEGFA Antibodies) and VEGFB associated sub-network, kinase insert domain receptor (KDR (show KDR Antibodies)), fibronectin 1 (FN1 (show FN1 Antibodies)), transforming growth factor beta induced (TGFBI) and proliferating cell nuclear antigen (PCNA (show PCNA Antibodies)) found to interact with at least two of the three hub genes.

7. Frameshift mutations of VEGFB gene is associated with stomach and colorectal cancers.

8. plasma VEGF (show VEGFA Antibodies) levels before treatment were lower in patients with schizophrenia and that their VEGF (show VEGFA Antibodies) levels increased after treatment.

9. fluid shear stress induces the synthesis of Insulin growth factor-2 and vascular endothelial growth factor (VEGF (show VEGF Antibodies)) B and D, which in turn transactivate MMP-12 (show MMP12 Antibodies).

10. MMP9 (show MMP9 Antibodies) may activate VEGF-B via PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling pathway.

Mouse (Murine) Vascular Endothelial Growth Factor B (VEGFB) interaction partners

1. Data suggest that dietary fatty acids create epigenetic/nutrigenomic changes in methylation levels of CpG island at Vegfb promoter and changes in Vegfb expression in white adipocytes in vivo and in vitro, with particular up-regulation of DNA methylation (show HELLS Antibodies) by linoleic acid; Vegfb promoter methylation levels are closely related to Vegfb gene expression in visceral and subcutaneous adipose tissue.

2. renal VEGF-B expression correlates with the severity of Diabetic Kidney Disease.

3. PGC-1alpha is a master metabolic sensor that regulates the expression of Vegfa (show VEGFA Antibodies) and Vegfb, coordinates blood vessels growth and fatty acid uptake with mitochondrial fatty acid oxidation.

4. These data therefore support a tightly controlled, paracrine signaling mechanism of VEGF-B to VEGFR1 (show FLT1 Antibodies).

5. VEGFB-Induced Vascular Remodeling in Adipose Tissue Requires VEGF (show VEGFA Antibodies)/VEGFR2 (show KDR Antibodies). VEGFB-Induced Vascular Remodeling Improves Insulin (show INS Antibodies) Supply, Signaling, and Function in Obese Mice.

6. VEGF-B is dispensable for normal cardiac function under unstressed conditions and for high fat diet-induced metabolic changes.

7. VEGF-B is a vascular remodeling factor promoting cancer metastasis.

8. Data indicate that vascular endothelial growth factor B knockout (Vegf-b-/-) mice showed impaired nerve repair with concomitant impaired trophic function.

9. Data indicate that VEGF-B is a high-affinity VEGFR-1 (show FLT1 Antibodies) ligand that, unlike PlGF (show PGF Antibodies), cannot efficiently induce signaling downstream of VEGFR-1 (show FLT1 Antibodies).

10. results demonstrate that the vascular endothelium can function as an efficient barrier to excess muscle lipid uptake even under conditions of severe obesity and type 2 diabetes, and that this barrier can be maintained by inhibition of VEGF-B signalling

Cow (Bovine) Vascular Endothelial Growth Factor B (VEGFB) interaction partners

1. PCR-SSCP and DNA sequencing methods were applied to reveal 3 SNPs and a duplication in the bovine VEGF-B gene among 675 samples belonging to three native Chinese cattle breeds.