Browse our anti-GRM7 (GRM7) Antibodies

Human Glutamate Receptor, Metabotropic 7 (GRM7) interaction partners

1. The results of this study indicate that the GRM7 rs9814881 might be associated with MDD in the Chinese Han population.

2. study to evaluate evidence for association between GRM7 and alcohol behaviors using an SNP approach, as well as a gene-based approach in two independent samples; Rs3749380 was suggestively associated with alcohol consumption in one sample with the minor T allele conferring risk; there was no evidence for association in the other sample

3. Autism spectrum disorder (ASD (show ARSD Antibodies)) as a synaptopathy is revealed to be pertained to aberrant glutamatergic neurotransmission. Glutamate (show GRIN1 Antibodies) receptor, metabotropic 7 (GRM7) is a receptor coding gene of this pathway.

4. GRM7 rs2133450 may have translational relevance as a predictor of response to risperidone in schizophrenia.

5. Multiple genetic models identified 1 significant locus, GRM7, for 2 hypertension-derived traits.

6. Study represents a genetic association test towards single variant and multi-markers interaction of GRM7 and GRM8 genes in both schizophrenia and major depressive disorders in Han Chinese population

7. Glutamate (show GRIN1 Antibodies) system genes have been associated with disease risk in recent analyses from the Psychiatric Genomics Consortium.

8. results indicate that the GRM7 SNPs rs13353402 and rs1531939 might be associated with schizophrenia in Chinese Han population.

9. results reported here do not support a role for GRM7 in ADHD

10. Copy number variants at GRM7 may have a role in the etiology of bipolar disorder.

Mouse (Murine) Glutamate Receptor, Metabotropic 7 (GRM7) interaction partners

1. mGlu7 may be a potential therapeutic target for multiple aspects of the Rett phenotype.

2. The mGlu7 receptor was found to be involved in a wide range of behavioral and physiological alterations in response to chronic psychosocial stress exposure.

3. This study provides evidence for mGlu7 receptor-mediated tonic modulation of a physiological function in vivo preventing synchronous and potentially pathological oscillations.

4. Analysis of mGluR7 (show GRM2 Antibodies) KO mice, c-Fos expression, and cerebral MMPIP microinjection indicate that inhibition of mGluR7 (show GRM2 Antibodies) impairs intermale aggression owing to information processing dysfunction within the bed nucleus of the stria terminalis

5. muscle does not appear to require high levels of SMN (show STMN1 Antibodies) above what is produced by two copies of SMN2 (show SMN1 Antibodies)

6. SAM68 (show KHDRBS1 Antibodies) is a physiological regulator of SMN2 (show SMN1 Antibodies) splicing in a spinal muscular atrophy mouse model.

7. Hyperoxia treatment increased the inclusion of SMN2 (show SMN1 Antibodies) exon 7 in skeletal muscles and resulted in improved motor function.

8. Elfn1 (show ELFN1 Antibodies) recruits mGluR7 (show GRM2 Antibodies) to synaptic sites.A trans interaction of Elfn1 (show ELFN1 Antibodies) and mGluR7 (show GRM2 Antibodies) controls targeted interneuron synapse development.

9. GRM7 regulates the phosphorylation of CREB protein and the expression of Yes-associated protein (YAP) by directly interacting with CaM, which subsequently regulates the expression of CyclinD1 and ultimately affects early cortical development.

10. Modeling the selective interaction between XAP044 and mGlu7's Venus flytrap domain, whose three-dimensional structure is already known, will facilitate future drug development supported by computer-assisted drug design