Browse our anti-POU Domain, Class 3, Transcription Factor 4 (POU3F4) Antibodies

Full name:: anti-POU Domain, Class 3, Transcription Factor 4 Antibodies (POU3F4)

On www.antibodies-online.com are 10 POU Domain, Class 3, Transcription Factor 4 (POU3F4) Antibodies from 9 different suppliers available. Additionally we are shipping POU Domain, Class 3, Transcription Factor 4 Proteins (8) and POU Domain, Class 3, Transcription Factor 4 Kits (5) and many more products for this protein. A total of 25 POU Domain, Class 3, Transcription Factor 4 products are currently listed.

Synonyms:: Brain-4, Brn-4, Brn4, DFN3, DFNX2, oct-9, OTF-9, Otf9, POU 2, pou2, pou3f4-a, RHS2, Slf, XlPOU-2, XlPOU2

list all antibodies	Gene Name	GeneID	UniProt
	POU3F4	5456	P49335
	POU3F4	29589	P62516
	POU3F4	18994	P62515
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Most Popular Reactivities for anti-POU Domain, Class 3, Transcription Factor 4 (POU3F4) Antibodies

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Relevant Pathways for anti-POU Domain, Class 3, Transcription Factor 4 Antibodies

Sensory Perception of Sound

More product categories related to POU Domain, Class 3, Transcription Factor 4 Antibody

Top referenced anti-POU Domain, Class 3, Transcription Factor 4 Antibodies

Cow (Bovine) Polyclonal POU3F4 Primary Antibody for WB - ABIN2792648 : Xia, Kikuchi, Minowa, Katori, Oshima, Noda, Ikeda: Late-onset hearing loss in a mouse model of DFN3 non-syndromic deafness: morphologic and immunohistochemical analyses. in Hearing research 2002 (PubMed)
Show all 2 Pubmed References
Human Polyclonal POU3F4 Primary Antibody for IHC, IHC (p) - ABIN4285272 : Diaz-de-Durana, Lau, Knee, Filippi, Londei, McNamara, Nasoff, DiDonato, Glynne, Herman: IL-2 immunotherapy reveals potential for innate beta cell regeneration in the non-obese diabetic mouse model of autoimmune diabetes. in PLoS ONE 2013 (PubMed)

More Antibodies against POU Domain, Class 3, Transcription Factor 4 Interaction Partners

Human POU Domain, Class 3, Transcription Factor 4 (POU3F4) interaction partners

POU3F4 mutations can be predicted by incomplete partition type III anomaly by radiological examination of the inner ear. All six of the patients showed mixed hearing loss, but none showed fluctuations in hearing, which may be related to the lack of vestibular aqueduct enlargement at the operculum.
Sequencing of the entire POU3F4 gene is recommended in patients with characteristic temporal bone malformations. Results of POU3F4 mutation testing are important not only for a proper genetic counseling, but also for adequate preparation and conduction of a surgical procedure.
A nonsense mutation is identified in a family displaying the pedigree consistent with X-linked recessive pattern in POU3F4 gene.
POU3F4 mutation in profoundly deaf patients may have poorer prognosis after cochlear implantation, than other types.
findings may greatly contribute to the elucidation of the roles of the Oct (show Plxna2 Antibodies) and Myc (show MYC Antibodies) proteins in osteoblast direct reprogramming. The results may also lead to establishment of novel regenerative therapy for various bone resorption diseases
Audiological, medical, and family histories were collected and family members interviewed to compare hearing thresholds and case histories between cases with mutations in SMPX (show SMPX Antibodies) versus POU3F4.
Our data suggest that different POU3F4 mutations might show different recurrence rate in siblings of the incomplete partition type III anomaly especially in East Asian population
POU3F4 mutations are associated with X-linked deafness
We concluded that the probable presence of the third window effect is not limited to the particular type of POU3F4 mutation.
Results show three novel mutations in the POU3F4 gene resulting in profound hearing loss in both humans and mice.

Xenopus laevis POU Domain, Class 3, Transcription Factor 4 (POU3F4) interaction partners

pou3f4 expression in inner ear might be under the control of distinct regulatory elements that fine-tune the spatio-temporal activity of this gene

Mouse (Murine) POU Domain, Class 3, Transcription Factor 4 (POU3F4) interaction partners

Brn4 substantially contributes to cochlear gap junction properties to maintain the proper EP in cochleae, similar to connexin-related deafness.
Efnb2 (show EFNB2 Antibodies) expression was attenuated in Pou3f4 hemizygous null mutants relative to control.
Results show three novel mutations in the POU3F4 gene resulting in profound hearing loss in both humans and mice.
This study indicated a model whereby Pou3f4 in the otic mesenchyme establishes an Eph/ephrin-mediated fasciculation signal that promotes inner radial bundle formation.
pou3f4 expression in inner ear might be under the control of distinct regulatory elements that fine-tune the spatio-temporal activity of this gene
The effects of Brn-4 on the neuronal differentiation and development of neural stem cells, were investigated.
a transcription factor targeted to the early mouse pancreas induces ectopic glucagon (show GCG Antibodies) gene expression
late-onset effect of Brn-4 deficiency on the hearing organ of the mouse. About one third of heterozygous female mice revealed late-onset profound deafness at the age of 1 year.
lack of role in regulating Pax6 (show PAX6 Antibodies) and Nkx2.2 (show Nkx2-2 Antibodies)
Tbx1 (show TBX1 Antibodies) and Brn4 function in signaling from the periotic mesenchyme to the otic vesicle to direct proper coiling of the cochlear duct.

POU Domain, Class 3, Transcription Factor 4 (POU3F4) Antigen Profile

Antigen Summary

This gene encodes a member of the POU-III class of neural transcription factors. This family member plays a role in inner ear development. The protein is thought to be involved in the mediation of epigenetic signals which induce striatal neuron-precursor differentiation. Mutations in this gene are associated with X chromosome-linked nonsyndromic mixed deafness.

Alternative names and synonyms associated with POU Domain, Class 3, Transcription Factor 4 (POU3F4)

POU class 3 homeobox 4 (POU3F4) antibody
POU class 3 homeobox 4 (pou3f4) antibody
POU class 3 homeobox 4 L homeolog (pou3f4.L) antibody
POU class 3 homeobox 4 (Pou3f4) antibody
POU domain, class 3, transcription factor 4 (Pou3f4) antibody

Brain-4 antibody
Brn-4 antibody
Brn4 antibody
DFN3 antibody
DFNX2 antibody
oct-9 antibody
OTF-9 antibody
Otf9 antibody
POU 2 antibody
pou2 antibody
pou3f4-a antibody
RHS2 antibody
Slf antibody
XlPOU-2 antibody
XlPOU2 antibody

Protein level used designations for POU3F4

, , , , , , , , , , , , , , , , , , , POU domain, class 3, transcription factor 4 POU class 3 homeobox 4 POU domain, class 3, transcription factor 4-like brain-specific homeobox/POU domain protein 4 octamer-binding transcription factor 9 POU 2 transcription factor POU domain, class 3, transcription factor 4-A Transcription factor POU2 XLPOU 2 xlPOU2 OTF-9 RHS2 class III POU protein brain-4 brn-4 oct-9 octamer-binding protein 9 Brain-specific homeobox/POU domain protein 4 POU homeodomain protein brain-4 class III POU-domain protein sex linked fidget

GENE ID	SPECIES
539732	Bos taurus
100152446	Sus scrofa
100036711	Xenopus (Silurana) tropicalis
100472065	Ailuropoda melanoleuca
5456	Homo sapiens
397929	Xenopus laevis
491988	Canis lupus familiaris
29589	Rattus norvegicus
101829289	Mesocricetus auratus
18994	Mus musculus

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Show all anti-POU Domain, Class 3, Transcription Factor 4 (POU3F4) Antibodies with Pubmed References