Browse our anti-Dedicator of Cytokinesis 1 (DOCK1) Antibodies

Full name:: anti-Dedicator of Cytokinesis 1 Antibodies (DOCK1)

On www.antibodies-online.com are 66 Dedicator of Cytokinesis 1 (DOCK1) Antibodies from 20 different suppliers available. Additionally we are shipping Dedicator of Cytokinesis 1 Proteins (4) and Dedicator of Cytokinesis 1 Kits (2) and many more products for this protein. A total of 74 Dedicator of Cytokinesis 1 products are currently listed.

Synonyms:: 9130006G06Rik, AI854900, ced5, D630004B07Rik, DOCK180, MGC140073, RGD1566072

list all antibodies	Gene Name	GeneID	UniProt
	DOCK1	313438
	DOCK1	1793	Q14185
	DOCK1	330662	Q8BUR4
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Most Popular Reactivities for anti-Dedicator of Cytokinesis 1 (DOCK1) Antibodies

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Relevant Pathways for anti-Dedicator of Cytokinesis 1 Antibodies

Signaling of Hepatocyte Growth Factor Receptor

More product categories related to Dedicator of Cytokinesis 1 Antibody

Top referenced anti-Dedicator of Cytokinesis 1 Antibodies

Human Polyclonal DOCK1 Primary Antibody for WB - ABIN257645 : Hasegawa, Kiyokawa, Tanaka, Nagashima, Gotoh, Shibuya, Kurata, Matsuda: DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane. in Molecular and cellular biology 1996 (PubMed)

More Antibodies against Dedicator of Cytokinesis 1 Interaction Partners

Zebrafish Dedicator of Cytokinesis 1 (DOCK1) interaction partners

A novel signaling cascade is identified in which ELMO1 (show ELMO1 Antibodies)/DOCK180 regulates vasculature formation in zebrafish.
The fusion of embryonic fast-twitch myoblasts requires the activities of Dock1 and the closely related Dock5 (show Dock5 Antibodies) protein.

Human Dedicator of Cytokinesis 1 (DOCK1) interaction partners

one statistically significant common variant in the DOCK1 gene was associated with DeltaBMI in GI cancer and COPD (show ARCN1 Antibodies) cases providing support for at least partially shared aetiology of DeltaBMI in complex diseases.
Taken together, these results indicate that DOCK1 is a critical regulator of the malignant phenotypes induced by Rac1(P29S), and suggest that targeting DOCK1 might be an effective approach to treat cancers associated with Rac1(P29S) mutation.
Data suggest that GPR124 (show GPR124 Antibodies) promotes cell adhesion via interaction with Elmo1 (show ELMO1 Antibodies)-Dock180 and intersectin 1 (show ITSN1 Antibodies)/2; this constitutes a previously unrecognized heteromeric complex that is putatively involved in GPR124 (show GPR124 Antibodies)-dependent adhesive/angiogenic responses in vascular endothelial cells. (GPR124 (show GPR124 Antibodies) = G-protein coupled receptor 124 (show GPR124 Antibodies); Elmo1 (show ELMO1 Antibodies) = ELMO domain-containing protein 1 (show ELMOD1 Antibodies); Dock180 = dedicator of cytokinesis protein 1 180 kDa)
stimulation of the DOCK180 pathway represents an alternative mechanism of PTP1B (show PTPN1 Antibodies) inhibitor-stimulated endothelial cell motility, which does not require concomitant VEGFR2 (show KDR Antibodies) activation as a prerequisite.
Thus, Elmo1 (show ELMO1 Antibodies) and Dock180 facilitate blood vessel formation by stabilization of the endothelium during angiogenesis.
High DOCK180 expression is associated with serous ovarian cancer.
our findings describe a novel mechanism by which EGFRvIII drives glioma tumorigenesis and invasion through protein kinase A-dependent phosphorylation of Dock180
findings indicate that a chemokine-controlled pathway, consisting of Galphai2, ELMO1/Dock180, Rac1 and Rac2, regulates the actin cytoskeleton during breast cancer metastasis
Dock180 could act as a pro-survival molecule in H9C2 cardiomyocytes via activation of its downstream pro-survival signaling molecule, AKT (show AKT1 Antibodies).
Solved is the solution structure of DOCK180 SH3 domain (show ITSN1 Antibodies), which shares similar target binding features with the SH3 domain (show ITSN1 Antibodies) of DOCK2 (show DOCK2 Antibodies).

Mouse (Murine) Dedicator of Cytokinesis 1 (DOCK1) interaction partners

Inactivation of Dock1 in mammary gland epithelial cells and activation of Stat3 (show STAT3 Antibodies) coincide with a delay in the initiation of mammary gland involution.
Dock1 and Dock5 (show Dock5 Antibodies) are not the important exchange factors regulating Rac (show AKT1 Antibodies) activity during the establishment and maintenance of the glomerular barrier
DOCK1-Rac (show AKT1 Antibodies) signaling as an HER2 (show ERBB2 Antibodies) effector pathway essential for HER2 (show ERBB2 Antibodies)-mediated breast cancer progression to metastasis.
The phospholipase D (show PLD Antibodies)-PA axis selectively controls dorsal ruffle formation by regulating DOCK1 localization.
The data demonstrate the ability of the SH3 domain (show ITSN1 Antibodies) of DOCK180 to interact with ELMO1 (show ELMO1 Antibodies), regardless of the presence of the polyproline-containing C-terminal end.
Dock1 has an essential role in embryonic development.
Results indicate that the combination of DOCK2 (show DOCK2 Antibodies) and DOCK180 plays a significant but not essential role in prevascular fetal thymus colonization.

Dedicator of Cytokinesis 1 (DOCK1) Antigen Profile

Antigen Summary

This gene product binds to the SH3 domain of CRK protein. It may regulate cell surface extension and may have a role in the cell surface extension of an engulfing cell around a dying cell during apoptosis.

Alternative names and synonyms associated with Dedicator of Cytokinesis 1 (DOCK1)

dedicator of cytokinesis 1 (dock1) antibody
dedicator of cytokinesis protein 1 (CpipJ_CPIJ002759) antibody
dedicator of cytokinesis 1 (DOCK1) antibody
dedicator of cytokinesis 11 (Dock11) antibody
dedicator of cytokinesis 11 (DOCK11) antibody
dedicator of cytokinesis 11 (dock11) antibody
dedicator of cyto-kinesis 1 (Dock1) antibody
dedicator of cytokinesis 1 (Dock1) antibody

9130006G06Rik antibody
AI854900 antibody
ced5 antibody
D630004B07Rik antibody
DOCK180 antibody
MGC140073 antibody
RGD1566072 antibody

Protein level used designations for DOCK1

dedicator of cytokinesis protein 1 , dedicator of cytokinesis 1 , dedicator of cytokinesis protein 1-like , dedicator of cytokinesis protein 11 , dedicator of cytokinesis 11 , Dedicator of cytokinesis protein 11 , dedicator of cytokinesis protein 11-like , 180 kDa protein downstream of CRK , DOwnstream of CrK , dedicator of cyto-kinesis 1 , DOCK180

GENE ID	SPECIES
572187	Danio rerio
6033953	Culex quinquefasciatus
100055697	Equus caballus
100375196	Saccoglossus kowalevskii
100411936	Callithrix jacchus
100467309	Ailuropoda melanoleuca
313438	Rattus norvegicus
492089	Canis lupus familiaris
537297	Bos taurus
100015415	Monodelphis domestica
100055441	Equus caballus
100081499	Ornithorhynchus anatinus
100354317	Oryctolagus cuniculus
100380692	Salmo salar
100411639	Callithrix jacchus
100457333	Pongo abelii
100477046	Ailuropoda melanoleuca
100498640	Xenopus (Silurana) tropicalis
309081	Rattus norvegicus
1793	Homo sapiens
537203	Bos taurus
330662	Mus musculus
423960	Gallus gallus
486934	Canis lupus familiaris

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Show all anti-Dedicator of Cytokinesis 1 (DOCK1) Antibodies with Pubmed References