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Browse our anti-CACNA2D2 (CACNA2D2) Antibodies

Full name:: anti-Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 2 Antibodies (CACNA2D2)

On www.antibodies-online.com are 51 Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 2 (CACNA2D2) Antibodies from 17 different suppliers available. Additionally we are shipping CACNA2D2 Proteins (10) and many more products for this protein. A total of 62 CACNA2D2 products are currently listed.

Synonyms:: a2d2, Cacna2d, du, LUAC11.1, mKIAA0558, td, torpid

list all antibodies	Gene Name	GeneID	UniProt
	CACNA2D2	9254	Q9NY47
	CACNA2D2	56808	Q6PHS9
	CACNA2D2	300992	Q8CFG6
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Most Popular Reactivities for anti-CACNA2D2 (CACNA2D2) Antibodies

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anti-Human CACNA2D2 Antibodies:

38 WB Antibodies

anti-Mouse (Murine) CACNA2D2 Antibodies:

26 WB Antibodies

anti-Rat (Rattus) CACNA2D2 Antibodies:

11 WB Antibodies

All available anti-CACNA2D2 Antibodies

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Relevant Pathways for anti-CACNA2D2 Antibodies

Skeletal Muscle Fiber Development

More product categories related to CACNA2D2 Antibody

Top referenced anti-CACNA2D2 Antibodies

Human Polyclonal CACNA2D2 Primary Antibody for WB - ABIN550315 : Kim, Kim, Lee, King, Chin: Rat brain expresses an alternatively spliced form of the dihydropyridine-sensitive L-type calcium channel alpha 2 subunit. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
Show all 3 Pubmed References
Human Monoclonal CACNA2D2 Primary Antibody for IF, ELISA - ABIN522733 : Pippucci, Parmeggiani, Palombo, Maresca, Angius, Crisponi, Cucca, Liguori, Valentino, Seri, Carelli: A novel null homozygous mutation confirms CACNA2D2 as a gene mutated in epileptic encephalopathy. in PLoS ONE 2013 (PubMed)

More Antibodies against CACNA2D2 Interaction Partners

Human Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 2 (CACNA2D2) interaction partners

show that the action of alpha2delta2 on tumor development occurs not only through a stimulation of proliferation
The investigation of single nucleotide polymorphisms in three genes that have a functional impact on the opioid response: OPRM1, ABCB1 and the calcium channel complex subunit CACNA2D2, is reported.
CACNA2D2 deletion/methylation is associated with cervical disease progression.
single nucleotide polymorphism identified
role in apoptosis in non-small cell lung cancer cells via association with alterations of the intracellular calcium signaling and disruption of mitochondria membrane integrity
In mice, targeted disruption of Cacna2d2 led to growth retardation, reduced life span, ataxia, enhanced susceptibility to seizures, and cardiac abnormalities. Cacna2d2 may be involved in hereditary cerebellar ataxias and epileptic disorders in humans.
Although transgenic du(2J)/+ mice have a marked reduction in alpha2delta-2 protein, they show no fall in Purkinje somatic calcium currents or increase in cerebellar tyrosine hydroxylase gene expression.

Mouse (Murine) Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 2 (CACNA2D2) interaction partners

Cacna2d2 is a developmental switch that limits axon growth and regeneration. Cacna2d2 gene deletion or silencing promoted axon growth in vitro.
Inner hair cells possess calcium channels that are essential for transmitting sound information into synaptic transmitter release. Voltage-gated calcium channels can coassemble with auxiliary subunit alpha2delta isoforms 1-4. We found that hair cells of the mouse express the auxiliary subunit alpha2delta2, which is needed for normal hearing thresholds. Using a mouse model with a mutant, nonfunctional alpha2delta2 prote...
all of the alpha(2)delta subunits studied, alpha(2)delta-1, alpha(2)delta-2, and alpha(2)delta-3, show all of the properties expected of glycosylphosphatidylinositol-anchored proteins, both when heterologously expressed and in native tissues.
We show that both mRNA and protein corresponding to this predicted transcript are expressed in du/du cerebellum and present in Purkinje cells
Cacna2d2 has a role in epilepsy and ataxia
In mice, targeted disruption of Cacna2d2 led to growth retardation, reduced life span, ataxia, enhanced susceptibility to seizures, and cardiac abnormalities. Cacna2d2 may be involved in hereditary cerebellar ataxias and epileptic disorders in humans.
Both alpha2delta-2 and CaV2.1 are normally associated with cholesterol-rich microdomains, and this influences their functionality.

CACNA2D2 Antigen Profile

Antigen Summary

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with CACNA2D2

calcium voltage-gated channel auxiliary subunit alpha2delta 2 (CACNA2D2) antibody
calcium channel, voltage-dependent, alpha 2/delta subunit 2 (Cacna2d2) antibody
calcium voltage-gated channel auxiliary subunit alpha2delta 2 (Cacna2d2) antibody

a2d2 antibody
Cacna2d antibody
du antibody
LUAC11.1 antibody
mKIAA0558 antibody
td antibody
torpid antibody

Protein level used designations for CACNA2D2

alpha 2 delta calcium channel subunit , gene 26 , voltage-dependent calcium channel subunit alpha-2/delta-2 , voltage-gated calcium channel subunit alpha-2/delta-2 , ducky , protein ducky , calcium channel, voltage dependent, alpha2/delta subunit 2

GENE ID	SPECIES
9254	Homo sapiens
56808	Mus musculus
300992	Rattus norvegicus

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Show all anti-Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 2 (CACNA2D2) Antibodies with Pubmed References

Human Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 2 (CACNA2D2) interaction partners

Mouse (Murine) Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 2 (CACNA2D2) interaction partners

Antigen Summary

Alternative names and synonyms associated with CACNA2D2

Protein level used designations for CACNA2D2