anti-Nucleoporin 98kDa Antibodies
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anti-Nucleoporin 98kDa (NUP98) (AA 1-466) antibody Primary Antibody
2
anti-Nucleoporin 98kDa (NUP98) (GLFG Motif), (N-Term) antibody Primary Antibody
2
anti-Nucleoporin 98kDa (NUP98) (FGxxN Motif), (N-Term) antibody Primary Antibody
2
anti-Nucleoporin 98kDa (NUP98) (N-Term) antibody Primary Antibody
anti-Nucleoporin 98kDa (NUP98) (AA 1-606) antibody Primary Antibody
anti-Nucleoporin 98kDa (NUP98) antibody Primary Antibody
anti-Nucleoporin 98kDa (NUP98) (N-Term) antibody Primary Antibody
anti-Nucleoporin 98kDa (NUP98) (N-Term) antibody Primary Antibody
anti-Nucleoporin 98kDa (NUP98) (N-Term) antibody Primary Antibody
anti-Nucleoporin 98kDa (NUP98) (AA 629-894) antibody Primary Antibody
Nucleoporin 98kDa (NUP98) Antigen Profile
Protein Summary
Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kDa precursor protein. This cleavage results in the 98 kDa nucleoporin as well as a 96 kDa nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kDa nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromosome translocations in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in several transcript variants\; however, not all variants have been fully described.
Alternative names and synonyms associated with Nucleoporin 98kDa (NUP98)
- Nucleoporin 98-96kD (Nup98-96) antibody
- nuclear pore complex protein Nup98-Nup96 (LOC408335) antibody
- nucleoporin 98 (NUP98) antibody
- nuclear pore complex protein Nup98-Nup96 (LOC587580) antibody
- nucleoporin 98kDa (NUP98) antibody
- nucleoporin 98 (Nup98) antibody
- nucleoporin 98 (nup98) antibody
- nucleoporin 98 L homeolog (nup98.L) antibody
- 4732457F17 antibody
- ADIR2 antibody
- AI849286 antibody
- CG10198 antibody
- CG10201 antibody
- Dmel\\CG10198 antibody
- GB12688 antibody
- im:7151238 antibody
- l(3)95BCd antibody
- Nup-98 antibody
- NUP96 antibody
- Nup 96 antibody
- NUP98 antibody
- Nup 98 antibody
- nup98-96 antibody
- Nup98-Nup96 antibody
- Nup98/96 antibody
- nup145 antibody
- NUP196 antibody
- zgc:63593 antibody
- zgc:113968 antibody
Protein level used designations for NUP98
CG10198-PA , CG10198-PC , CG10198-PD , Nup98 , Nup98-96-PA , Nup98-96-PC , Nup98-96-PD , nucleoporin 98 , nucleoporin 98-96 , nucleoporin98-96 , nucleoporin 98kD , nucleoporin 98kDa , nuclear pore complex protein Nup98-Nup96-like , nuclear pore complex protein Nup98-Nup96 , 98 kDa nucleoporin , nuclear pore complex protein Nup98 , nucleoporin Nup98 , GLFG-repeat containing nucleoporin , Nup98-Nup96
| GENE ID | SPECIES |
|---|---|
| 42816 | Drosophila melanogaster |
| 408335 | Apis mellifera |
| 450971 | Pan troglodytes |
| 587580 | Strongylocentrotus purpuratus |
| 100016427 | Monodelphis domestica |
| 100052986 | Equus caballus |
| 100090367 | Ornithorhynchus anatinus |
| 100414799 | Callithrix jacchus |
| 100475098 | Ailuropoda melanoleuca |
| 100522560 | Sus scrofa |
| 269966 | Mus musculus |
| 81738 | Rattus norvegicus |
| 777756 | Danio rerio |
| 430616 | Gallus gallus |
| 4928 | Homo sapiens |
| 476822 | Canis lupus familiaris |
| 540004 | Bos taurus |
| 100343626 | Oryctolagus cuniculus |
| 446233 | Xenopus laevis |
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