Browse our PLA2G2A Proteins (PLA2G2A)

The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.

• phospholipase A2 group IIA (PLA2G2A)
• phospholipase A2 group IIA (Pla2g2a)
• phospholipase A2, group IIA (platelets, synovial fluid) (Pla2g2a)
• phospholipase A2, group IIA (platelets, synovial fluid) (PLA2G2A)

• EF protein
• Mom1 protein
• Pla2 protein
• PLA2B protein
• PLA2L protein
• Show all synonym aliases
• PLA2S protein
• PLAS1 protein
• sPLA2 protein
• sPla2-IIA protein

GIIC sPLA2 , NPS-PLA2 , group IIA phospholipase A2 , non-pancreatic secretory phospholipase A2 , phosphatidylcholine 2-acylhydrolase 2A , phospholipase A2, membrane associated , eted enzyme type IIA phospholipase A2 , platelet phospholipase A2 , enhancing factor , modifier of Min1 , non-pancreatic secreted type II phospholipase A2 , secretory group II phospholipase A2 , typeII phospholipase A2